Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5809506 | 1.00 | RAB9A (0.48) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL7708937 | 0.82 | MAPT (0.60) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL7708935 | 0.82 | MAPT (0.60) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL596803 | 0.80 | MEN1 (0.67) | KMT2AMAPTMEN1ALDH1A1THRB | |
| SCHEMBL596372 | 0.80 | MEN1 (0.51) | KMT2AMEN1ALDH1A1THRBHDAC3 | |
| SCHEMBL596371 | 0.80 | MEN1 (0.51) | KMT2AMEN1ALDH1A1THRBHDAC3 | |
| SCHEMBL596802 | 0.80 | MEN1 (0.67) | KMT2AMAPTMEN1ALDH1A1THRB | |
| SCHEMBL4556769 | 0.79 | HDAC1 (0.61) | KMT2AMEN1HDAC3HDAC4HDAC1 | |
| SCHEMBL5486185 | 0.77 | TRPA1 (0.67) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL14437429 | 0.77 | TRPA1 (0.67) | RAB9ANPC1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006125293-A1 | DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID | ANTIBE THERAPEUTICS INC. (CA) | 2006-11-30 | — | — | WO | disclosed |