Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4556944 | 1.00 | MEN1 (0.40) | MEN1KMT2ALMNACYP3A4CYP2D6 | |
| SCHEMBL4454108 | 0.82 | MMP1 (0.43) | MEN1KMT2AMMP1MMP9MMP13 | |
| SCHEMBL13724235 | 0.77 | CETP (0.41) | CYP3A4TSHRMMP1MMP9MMP13 | |
| SCHEMBL3595900 | 0.74 | MEN1 (0.43) | MEN1KMT2ALMNACYP3A4CYP2D6 | |
| SCHEMBL2023058 | 0.74 | MEN1 (0.43) | MEN1KMT2ALMNACYP3A4CYP2D6 | |
| SCHEMBL4447822 | 0.71 | RIPK1 (0.37) | MEN1KMT2ALMNACYP3A4CYP2D6 | |
| SCHEMBL31564894 | 0.69 | KCNH2 (0.50) | MEN1KMT2AMMP1MMP9MMP13 | |
| SCHEMBL10830752 | 0.69 | CA12 (0.40) | MEN1KMT2AALOX15TSHRMMP1 | |
| SCHEMBL1753870 | 0.68 | HDAC6 (0.58) | LMNALTB4R2PKMHDAC1HDAC6 | |
| SCHEMBL567235 | 0.68 | KMT2A (0.54) | MEN1KMT2ALMNATSHRRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120965-A1 | N-HALOGENATED AMINO COMPOUNDS AND DERIVATIVES | Novabay Pharmaceuticals, Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008083347-A1 | N-HALOGENATED AMINO COMPOUNDS AND DERIVATIVES | NOVABAY PHARMACEUTICALS, INC. (US) | 2008-07-10 | — | — | WO | disclosed |