Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4556943 | 0.71 | MEN1 (0.40) | RIPK1CTSKLMNAMEN1KMT2A | |
| SCHEMBL4556944 | 0.71 | MEN1 (0.40) | RIPK1CTSKLMNAMEN1KMT2A | |
| SCHEMBL3595900 | 0.71 | MEN1 (0.43) | RIPK1LMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL2023058 | 0.71 | MEN1 (0.43) | RIPK1LMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL2310726 | 0.67 | MEN1 (0.49) | RIPK1LMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL2211148 | 0.64 | MMP8 (0.40) | RIPK1LMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL29170853 | 0.63 | SLC6A2 (0.41) | RIPK1POLBLMNAMEN1KMT2A | |
| SCHEMBL14910072 | 0.63 | RIPK1 (0.43) | RIPK1POLBLMNAMEN1KMT2A | |
| SCHEMBL28766213 | 0.63 | CTSK (0.45) | POLBCTSKCYP3A4CYP2C19TSHR | |
| SCHEMBL6472726 | 0.63 | SMN1; SMN2 (0.53) | LMNACYP3A4CYP2C19HIF1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120965-A1 | N-HALOGENATED AMINO COMPOUNDS AND DERIVATIVES | Novabay Pharmaceuticals, Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008083347-A1 | N-HALOGENATED AMINO COMPOUNDS AND DERIVATIVES | NOVABAY PHARMACEUTICALS, INC. (US) | 2008-07-10 | — | — | WO | disclosed |