Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11184414 | 0.87 | KDM4E (0.52) | HSD17B10HPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL29291851 | 0.83 | HMGB1 (0.46) | HSD17B10HPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL6826461 | 0.81 | HMGB1 (0.38) | HSD17B10HPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL125964 | 0.80 | KDM4E (0.56) | HSD17B10HPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL2790721 | 0.77 | PDE10A (0.45) | HSD17B10HPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL2468887 | 0.77 | POLB (0.48) | HSD17B10HPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL31414101 | 0.75 | HSD17B10 (0.54) | HSD17B10HPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL4415520 | 0.75 | HSD17B10 (0.54) | HSD17B10HPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL29260803 | 0.75 | DHODH (0.55) | HSD17B10HPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL27857954 | 0.73 | MEN1 (0.58) | HSD17B10HPGDKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | claimed |
| US-5122361-A | 2-Pyrrolidinylmethylcarboxamido-2,3-dihydrobenzofuran type compounds | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1992-06-16 | — | — | US | disclosed |