SCHEMBL31414101

SCHEMBL31414101

O=C(O)c1c(C(=O)O)c(O)c2ccccc2c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.54
HPGD P15428 3/20 0.54
KDM4E B2RXH2 3/20 0.54
ALDH1A1 P00352 3/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
CYP1A2 P05177 1/20 0.54
GLA P06280 1/20 0.54
CYP2C19 P33261 1/20 0.54
CYP2C9 P11712 2/20 0.54
TSHR P16473 2/20 0.54
THRB P10828 1/20 0.54
ALOX12 P18054 1/20 0.54
ATIC P31939 1/20 0.54
DHODH Q02127 3/20 0.50
PDE10A Q9Y233 2/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4415520 1.00 HSD17B10 (0.54) HSD17B10HPGDKDM4EALDH1A1MEN1
SCHEMBL27572021 0.93 HSD17B10 (0.48) HSD17B10HPGDKDM4EALDH1A1MEN1
SCHEMBL28261469 0.90 DHODH (0.52) HSD17B10HPGDKDM4EALDH1A1MEN1
SCHEMBL344711 0.90 HSD17B10 (0.50) HSD17B10HPGDKDM4EALDH1A1MEN1
SCHEMBL901598 0.88 HSD17B10 (0.48) HSD17B10HPGDKDM4EALDH1A1MEN1
SCHEMBL2477681 0.87 HSD17B10 (0.58) HSD17B10HPGDKDM4EALDH1A1MEN1
SCHEMBL7537511 0.85 DHODH (0.52) HSD17B10HPGDKDM4EALDH1A1MEN1
SCHEMBL29291851 0.84 HMGB1 (0.46) HSD17B10HPGDKDM4EALDH1A1MEN1
SCHEMBL5162563 0.84 PDE10A (0.50) HSD17B10HPGDKDM4EALDH1A1MEN1
SCHEMBL29260803 0.84 DHODH (0.55) HSD17B10HPGDKDM4EALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119570018-A Arc-resistant polyaryletherketone matrix and preparation method thereof, and arc-resistant composite material and preparation method thereof 江苏君华特种高分子材料股份有限公司 2025-03-07 CN claimed
CN-119570018-A Arc-resistant polyaryletherketone matrix and preparation method thereof, and arc-resistant composite material and preparation method thereof 江苏君华特种高分子材料股份有限公司 2025-03-07 CN disclosed