SCHEMBL4557142

SCHEMBL4557142

Sc1c(-c2ccccc2)ccc(-c2ccc(-c3ccccc3)cc2)c1S

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
HSD17B10 Q99714 3/20 0.43
MAPK1 P28482 2/20 0.43
BCL2L1 Q07817 2/20 0.43
TAAR1 Q96RJ0 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MMP3 P08254 1/20 0.43
BACE1 P56817 1/20 0.42
MEN1 O00255 1/20 0.41
APAF1 O14727 1/20 0.41
NPC1 O15118 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
THRB P10828 1/20 0.41
XBP1 P17861 1/20 0.41
PTBP1 P26599 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3183499 0.80 ALDH1A1 (0.48) ALDH1A1HSD17B10MAPK1BCL2L1TDP1
SCHEMBL11816809 0.79 LMNA (0.40) ALDH1A1HSD17B10MAPK1BCL2L1BACE1
Tannin Pyrogallol SCHEMBL28605084 0.78 ALDH1A1 (0.82) ALDH1A1HSD17B10MAPK1BCL2L1TAAR1
SCHEMBL17454568 0.77 ALDH1A1 (0.46) ALDH1A1HSD17B10MAPK1BCL2L1TAAR1
SCHEMBL10710026 0.77 MEN1 (0.47) ALDH1A1HSD17B10MAPK1BCL2L1TAAR1
SCHEMBL456551 0.76 ALDH1A1 (0.47) ALDH1A1HSD17B10MAPK1BCL2L1BACE1
SCHEMBL12609346 0.76 ALDH1A1 (0.47) ALDH1A1HSD17B10MAPK1BCL2L1TAAR1
SCHEMBL5951150 0.76 ALDH1A1 (0.64) ALDH1A1HSD17B10MAPK1BCL2L1TAAR1
Tannin Pyrogallol SCHEMBL13685561 0.76 ALDH1A1 (0.64) ALDH1A1HSD17B10MAPK1BCL2L1TAAR1
SCHEMBL30257106 0.76 ALDH1A1 (0.64) ALDH1A1HSD17B10MAPK1BCL2L1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7550216-B2 Composite solid polymer electrolyte membranes FOSTER-MILLER, INC. (US) 2009-06-23 US claimed
EP-1774610-A2 SOLID POLYMER ELECTROLYTE MEMBRANES FOSTER-MILLER, INC. (US) 2007-04-18 EP claimed
WO-2006076031-A9 SOLID POLYMER ELECTROLYTE MEMBRANES FOSTER MILLER INC (US) 2007-01-04 WO claimed
WO-2006076031-A2 SOLID POLYMER ELECTROLYTE MEMBRANES FOSTER-MILLER, INC. (US) 2006-07-20 WO claimed
WO-2006073474-A2 COMPOSITE SOLID POLYMER ELECTROLYTE MEMBRANES FOSTER-MILLER, INC. (US) 2006-07-13 WO claimed
US-20050031925-A1 Composite solid polymer electrolyte membranes FOSTER-MILLER INC. 2005-02-10 US claimed
EP-1774610-A2 SOLID POLYMER ELECTROLYTE MEMBRANES FOSTER-MILLER, INC. (US) 2007-04-18 EP disclosed
WO-2006076031-A9 SOLID POLYMER ELECTROLYTE MEMBRANES FOSTER MILLER INC (US) 2007-01-04 WO disclosed
WO-2006076031-A2 SOLID POLYMER ELECTROLYTE MEMBRANES FOSTER-MILLER, INC. (US) 2006-07-20 WO disclosed
US-20060003210-A1 Solid polymer electrolyte membranes FOSTER-MILLER, INC. 2006-01-05 US disclosed