Carbamic Acid

Carbamic Acid

SCHEMBL4557178

CCCCOc1oc2ccc(I)cc2c(=O)c1CCC.NC(=O)O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 2/20 0.41
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 3/20 0.38
HPGD P15428 3/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
HSD17B10 Q99714 2/20 0.38
ACSL1 P33121 2/20 0.37
ACSL6 Q9UKU0 2/20 0.37
MTNR1A P48039 2/20 0.36
MTNR1B P49286 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CYP2C9 P11712 1/20 0.36
KDM4A O75164 1/20 0.36
KDM5A P29375 1/20 0.36
ING2 Q9H160 1/20 0.36
APP P05067 1/20 0.35
PGAM1 P18669 1/20 0.35
THRA P10827 1/20 0.34
THRB P10828 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69420 0.93 APP (0.39) LTB4RKDM4EALDH1A1HPGDNPC1
SCHEMBL29451185 0.93 APP (0.39) LTB4RKDM4EALDH1A1HPGDNPC1
SCHEMBL483576 0.90 LTB4R (0.41) LTB4RKDM4EALDH1A1HPGDNPC1
SCHEMBL344030 0.87 CYP2A6 (0.37) LTB4RKDM4EALDH1A1HPGDNPC1
SCHEMBL3657351 0.85 LTB4R (0.37) LTB4RKDM4EALDH1A1HPGDNPC1
SCHEMBL343039 0.85 KDM4E (0.37) LTB4RKDM4EALDH1A1HPGDNPC1
SCHEMBL13038104 0.82 ALDH1A1 (0.39) LTB4RKDM4EALDH1A1HPGDNPC1
SCHEMBL747965 0.81 APP (0.33) LTB4RKDM4EALDH1A1HPGDNPC1
SCHEMBL6029914 0.81 APP (0.43) KDM4EALDH1A1HPGDNPC1RAB9A
SCHEMBL19908186 0.80 MAPT (0.46) LTB4RKDM4EALDH1A1HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2114159-A2 PESTICIDAL MIXTURES BASED ON AZOLOPYRIMIDINYLAMINES DERIVATIVES AND INSECTICIDES BASF SE (DE) 2009-11-11 EP disclosed
WO-2008092759-A2 PESTICIDAL MIXTURES BASED ON AZOLOPYRIMIDINYLAMINES DERIVATIVES AND INSECTICIDES BASF SE (DE) 2008-08-07 WO disclosed