Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69420 | 0.94 | APP (0.39) | APPCA12CA1CA2CA6 | |
| SCHEMBL29451185 | 0.94 | APP (0.39) | APPCA12CA1CA2CA6 | |
| SCHEMBL483576 | 0.92 | LTB4R (0.41) | APPCA12CA1CA2CA6 | |
| SCHEMBL3657351 | 0.92 | LTB4R (0.37) | CYP2A6APPCA12CA1CA2 | |
| SCHEMBL343039 | 0.92 | KDM4E (0.37) | CYP2A6APPCA12CA9LTB4R | |
| SCHEMBL747965 | 0.88 | APP (0.33) | APPCA12CA1CA9LTB4R | |
| SCHEMBL6029914 | 0.88 | APP (0.43) | APPKDM4EALDH1A1HPGDMAPT | |
| Carbamic Acid SCHEMBL4557178 | 0.87 | LTB4R (0.41) | APPLTB4RKDM4EALDH1A1HPGD | |
| SCHEMBL6030100 | 0.87 | GABRA1 (0.34) | APPLTB4RKDM4EALDH1A1HPGD | |
| SCHEMBL3668856 | 0.86 | APP (0.33) | APPLTB4RKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 324 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160150785-A1 | Synergistic Fungicidal Active Substance Combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-02 | — | — | US | claimed |
| WO-2014170354-A1 | INSECTICIDAL AND/OR FUNGICIDAL SYNERGISTIC COMBINATIONS OF PHTHALDIAMIDE DERIVATIVES AND A FURTHER ACTIVE INGREDIENT | BAYER CROPSCIENCE AG (DE) | 2014-10-23 | — | — | WO | claimed |
| US-20140213557-A1 | Active Compound Combinations | BAYER CROPSCIENCE AG (DE) | 2014-07-31 | — | — | US | claimed |
| US-20130196981-A1 | Synergistic Fungicidal Active Substance Combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-08-01 | — | — | US | claimed |
| EP-2023724-B8 | SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2012-06-06 | — | — | EP | claimed |
| EP-2453750-A2 | SYNERGISTIC ACTIVE SUBSTANCE COMBINATIONS CONTAINING PHENYL TRIAZOLES | Bayer CropScience AG (DE) | 2012-05-23 | — | — | EP | claimed |
| US-20120035050-A1 | Synergistic Combinations Of Active Ingredients | BAYER CROPSCIENCE AG (DE) | 2012-02-09 | — | — | US | claimed |
| US-20120015910-A1 | Synergistic fungicidal active substance combinations | BAYER CROPSCIENCE AG (DE) | 2012-01-19 | — | — | US | claimed |
| US-20110166109-A1 | Synergistic Active Compound Combinations Comprising Phenyltriazoles | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | US | claimed |
| US-20110152097-A1 | Active Compound Combinations | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | claimed |
| US-20070060579-A1 | Synergistic fungicidal active substance combinations | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | claimed |
| WO-2006131230-A2 | ACTIVE SUBSTANCE COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2006-12-14 | — | — | WO | claimed |
| WO-2006131246-A1 | FUNGICIDAL ACTIVE SUBSTANCE COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2006-12-14 | — | — | WO | claimed |
| WO-2006105888-A2 | SYNERGISTIC FUNGICIDAL ACTIVE SUBSTANCE COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2006-10-12 | — | — | WO | claimed |
| EP-1677598-A2 | SYNERGISTIC FUNGICIDAL ACTIVE COMBINATIONS | Bayer CropScience Aktiengesellschaft (DE) | 2006-07-12 | — | — | EP | claimed |
| EP-1675461-A1 | SYNERGISTIC FUNGICIDAL ACTIVE SUBSTANCE COMBINATIONS | Bayer CropScience AG (DE) | 2006-07-05 | — | — | EP | claimed |
| WO-2005058036-A1 | FUNGICIDE COMPOSITION COMPRISING AT LEAST ONE FUNGICIDAL IODOCHROMONE DERIVATIVE AND AT LEAST ONE FUNGICIDAL PYRIMIDINE DERIVATIVE | BAYER CROPSCIENCE SA (FR) | 2005-06-30 | — | — | WO | claimed |
| EP-1543723-A1 | Fungicide composition comprising at least one fungicidal iodochromone derivative and at least one fungicidal pyrimidine derivative | Bayer CropScience S.A. (FR) | 2005-06-22 | — | — | EP | claimed |
| WO-2005041653-A2 | SYNERGISTIC FUNGICIDAL ACTIVE COMBINATIONS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-05-12 | — | — | WO | claimed |
| WO-2005034628-A1 | SYNERGISTIC FUNGICIDAL ACTIVE SUBSTANCE COMBINATIONS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-04-21 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152097-A1 | Active Compound Combinations | AGXT, GLUL, GMNN | CYP2A6 1020/4885APP 2561/4885CA12 2801/4885 |
| US-20160150785-A1 | Synergistic Fungicidal Active Substance Combinations | CYP1A2, CAT, CYP51A1 | CYP2A6 75/4885APP 4608/4885CA12 1392/4885 |
| US-20140213557-A1 | Active Compound Combinations | AGXT, GLUL, GMNN | CYP2A6 1020/4885APP 2561/4885CA12 2801/4885 |
| US-20120035050-A1 | Synergistic Combinations Of Active Ingredients | C1S, MAN2B1, MANBA | CYP2A6 1996/4885APP 1465/4885CA12 1612/4885 |
| US-20110166109-A1 | Synergistic Active Compound Combinations Comprising Phenyltriazoles | NAT1, ACAT1, CAT | CYP2A6 1121/4885APP 790/4885CA12 2618/4885 |
| US-20070060579-A1 | Synergistic fungicidal active substance combinations | CYP51A1, CYP1A2, CYP4X1 | CYP2A6 68/4885APP 4483/4885CA12 1316/4885 |
| US-20120015910-A1 | Synergistic fungicidal active substance combinations | CYP51A1, CYP1A2, CYP4X1 | CYP2A6 68/4885APP 4483/4885CA12 1316/4885 |
| US-20130196981-A1 | Synergistic Fungicidal Active Substance Combinations | CYP51A1, CYP1A2, CYP4X1 | CYP2A6 68/4885APP 4483/4885CA12 1316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.