Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31265678 | 0.70 | NR1H4 (0.30) | — | |
| SCHEMBL31616743 | 0.69 | NCEH1 (0.36) | PTGDR2MEN1KMT2ANCEH1 | |
| SCHEMBL31345640 | 0.68 | CES2 (0.36) | HTTMEN1KMT2ALMNAMAPT | |
| SCHEMBL28627336 | 0.68 | KIF11 (0.33) | HTTMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL27947755 | 0.67 | PTGDR2 (0.40) | KDM4EPTGDR2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18475447 | 0.67 | ALOX12 (0.40) | L3MBTL1HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28522616 | 0.67 | POLB (0.33) | PTGDR2MEN1KMT2AMAPT | |
| SCHEMBL31265698 | 0.67 | POLB (0.33) | MEN1KMT2AMAPT | |
| SCHEMBL29177192 | 0.67 | KMT2A (0.34) | L3MBTL1ALOX15GFERADAM17HTT | |
| SCHEMBL28913028 | 0.67 | PTGDR2 (0.30) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009144632-A1 | NOVEL COMPOUNDS | PFIZER LIMITED (GB) | 2009-12-03 | — | — | WO | disclosed |