Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LGMN | Q99538 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9083863 | 0.91 | MAPT (0.44) | TACR2HSD17B10ATMALDH1A1SMN1; SMN2 | |
| SCHEMBL17893619 | 0.83 | LGMN (0.44) | HSD17B10ATMALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4557553 | 0.82 | TACR2 (0.40) | TACR2HSD17B10ATMALDH1A1SMN1; SMN2 | |
| SCHEMBL9948445 | 0.79 | KMT2A (0.50) | HSD17B10ALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL17893639 | 0.79 | HSD17B10 (0.43) | TACR2HSD17B10ATMALDH1A1SMN1; SMN2 | |
| SCHEMBL6351916 | 0.79 | MAPT (0.45) | HSD17B10ATMALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6349573 | 0.77 | CASP1 (0.60) | ALDH1A1MAPTLMNANPC1KMT2A | |
| SCHEMBL9083987 | 0.76 | MAPT (0.43) | HSD17B10ATMALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL12490953 | 0.76 | PTPN11 (0.43) | TACR2HSD17B10ATMALDH1A1SMN1; SMN2 | |
| SCHEMBL17673774 | 0.76 | MAPT (0.56) | ALDH1A1SMN1; SMN2MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550240-A | Piperazinyl-bis(alkylamino)pyrimidine derivatives and process for preparing same | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1996-08-27 | — | — | US | disclosed |
| US-5547949-A | INHIBITING PEROXIDATION OF LIPIDS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1996-08-20 | — | — | US | disclosed |
| EP-0646126-A1 | NOVEL STEROIDS WITH PREGNANE SKELETON, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1995-04-05 | — | — | EP | disclosed |
| EP-0644882-A1 | NOVEL PIPERZINYL-BIS(ALKYLAMINO)PYRIMIDINE DERIVATIVES AND PROCESS FOR PREPARING SAME | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1995-03-29 | — | — | EP | disclosed |
| WO-1993025570-A1 | NOVEL STEROIDS WITH PREGNANE SKELETON, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1993-12-23 | — | — | WO | disclosed |
| WO-1993025539-A1 | NOVEL PIPERZINYL-BIS(ALKYLAMINO)PYRIMIDINE DERIVATIVES AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1993-12-23 | — | — | WO | disclosed |