Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592790 | 0.84 | ADORA2A (0.47) | HPGDHTR2AADORA2APDE4DMEN1 | |
| SCHEMBL29286377 | 0.83 | TK1 (0.46) | HPGDHTR2AHPRT1MEN1KMT2A | |
| SCHEMBL20472317 | 0.82 | SMN1; SMN2 (0.45) | LMNAHTR2APOLBADORA2AHPRT1 | |
| SCHEMBL28712711 | 0.82 | PNP (0.42) | HPGDLMNAHTR2AHPRT1MEN1 | |
| SCHEMBL20509476 | 0.81 | HPRT1 (0.46) | HPGDHPRT1PNP | |
| SCHEMBL28025674 | 0.81 | HPGD (0.41) | HPGDLMNAHTR2AHPRT1MEN1 | |
| SCHEMBL27710751 | 0.81 | ADORA2A (0.52) | ADORA2APDE4DMEN1KMT2AALDH1A1 | |
| SCHEMBL1665132 | 0.81 | TK1 (0.47) | HPGDLMNAHTR2AHPRT1MEN1 | |
| SCHEMBL19413462 | 0.79 | ADORA2A (0.49) | HPGDADORA2AHPRT1MEN1KMT2A | |
| SCHEMBL48223 | 0.78 | PNP (0.42) | HPGDHTR2AHPRT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11130987-B2 | Direct detection of RNA by surface initiated enzymatic polymerization | SENTILUS HOLDCO, LLC (US) | 2021-09-28 | — | — | US | disclosed |
| US-20170058329-A1 | DIRECT DETECTION OF RNA BY SURFACE INITIATED ENZYMATIC POLYMERIZATION | SENTILUS HOLDCO, LLC | 2017-03-02 | — | — | US | disclosed |
| WO-2015081088-A1 | DIRECT DETECTION OF RNA BY SURFACE INITIATED ENZYMATIC POLYMERIZATION | IMMUCOR, GTT DIAGNOSTICS, INC. (US) | 2015-06-04 | — | — | WO | disclosed |
| US-8859490-B2 | Peptide nucleic acid monomers and oligomers | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-10-14 | — | — | US | disclosed |
| US-20120070909-A1 | LABEL-FREE METHOD FOR DETECTING PRESENCE OR ABSENCE OF NUCLEIC ACIDS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-03-22 | — | — | US | disclosed |
| US-20120065364-A2 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-03-15 | — | — | US | disclosed |
| US-20110245458-A1 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | NANYANG TECHONOLOGICAL UNIVERSITY (SG) | 2011-10-06 | — | — | US | disclosed |
| WO-2010093334-A1 | LABEL-FREE METHOD FOR DETECTING PRESENCE OR ABSENCE OF NUCLEIC ACIDS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010027326-A1 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2010-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065364-A2 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | SIN3A, POLR2H, CYTH3 | HPGD 4559/4885LMNA 1093/4885HTR2A 2360/4885 |
| US-20110245458-A1 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | SIN3A, POLR2H, CYTH3 | HPGD 4559/4885LMNA 1093/4885HTR2A 2360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.