SCHEMBL4557946

SCHEMBL4557946

CCCCCc1ccc(O)c(C)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.59
ESR2 Q92731 2/20 0.59
KAT8 Q9H7Z6 2/20 0.58
IGF1R P08069 2/20 0.55
ALOX15 P16050 2/20 0.55
ADRA2A P08913 2/20 0.55
ADORA3 P0DMS8 2/20 0.55
TACR2 P21452 2/20 0.55
SLC6A2 P23975 2/20 0.55
SLC6A4 P31645 2/20 0.55
SLC6A3 Q01959 2/20 0.55
CYP3A4 P08684 2/20 0.55
PTGS2 P35354 2/20 0.55
KDM4E B2RXH2 1/20 0.55
ALDH1A1 P00352 1/20 0.55
LMNA P02545 1/20 0.55
SHBG P04278 1/20 0.55
TP53 P04637 1/20 0.55
HSPD1 P10809 1/20 0.55
ADRB3 P13945 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28358828 0.98 KAT8 (0.61) ESR1ESR2KAT8IGF1RALOX15
SCHEMBL28358832 0.98 KAT8 (0.61) ESR1ESR2KAT8IGF1RALOX15
SCHEMBL9772343 0.98 KAT8 (0.61) ESR1ESR2KAT8IGF1RALOX15
SCHEMBL4839074 0.98 KAT8 (0.61) ESR1ESR2KAT8IGF1RALOX15
SCHEMBL10357818 0.98 KAT8 (0.61) ESR1ESR2KAT8IGF1RALOX15
SCHEMBL6351263 0.98 KAT8 (0.61) ESR1ESR2KAT8IGF1RALOX15
SCHEMBL28358761 0.98 KAT8 (0.61) ESR1ESR2KAT8IGF1RALOX15
SCHEMBL7247638 0.98 KAT8 (0.61) ESR1ESR2KAT8IGF1RALOX15
SCHEMBL21612711 0.98 KAT8 (0.61) ESR1ESR2KAT8IGF1RALOX15
SCHEMBL6056660 0.98 KAT8 (0.61) ESR1ESR2KAT8IGF1RALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101305030-B Polyfunctional poly(arylene ether) method GEN ELECTRIC 2011-07-13 CN claimed
CN-101326215-A Poly (arylene ether) copolymer GEN ELECTRIC (US) 2008-12-17 CN claimed
CN-101305030-A Polyfunctional poly(arylene ether) method GEN ELECTRIC (US) 2008-11-12 CN claimed
CN-111032606-B Bisphenol composition and method for producing same, and polycarbonate resin and method for producing same 三菱化学株式会社 2024-01-30 CN disclosed
CN-113574042-B Bisphenol composition and polycarbonate resin 三菱化学株式会社 2023-10-13 CN disclosed
CN-113574041-B Bisphenol production method and polycarbonate resin production method 三菱化学株式会社 2023-10-13 CN disclosed
CN-113544177-B Terminal (meth) acrylate polycarbonate oligomers 本州化学工业株式会社 2023-04-18 CN disclosed
CN-111344161-B Non-pneumatic tire 株式会社普利司通 2022-03-22 CN disclosed
CN-113574090-A Bisphenol composition and polycarbonate resin 三菱化学株式会社 2021-10-29 CN disclosed
CN-113574041-A Method for producing bisphenol and method for producing polycarbonate resin 三菱化学株式会社 2021-10-29 CN disclosed
CN-113574042-A Bisphenol composition and polycarbonate resin 三菱化学株式会社 2021-10-29 CN disclosed
US-20030166644-A1 Compounds and uses thereof for decreasing activity of hormone-sensitive lipase NOVO NORDISK A/S (DK) 2003-09-04 US disclosed
WO-2003051841-A2 COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2003-06-26 WO disclosed
WO-2003051842-A2 COMPOSITIONS DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2003-06-26 WO disclosed
EP-0164477-A1 Polycarbonates exhibiting improved heat resistance GENERAL ELECTRIC COMPANY (US) 1985-12-18 EP disclosed
US-4438284-A Catalysts for oxidative coupling of phenols THE DOW CHEMICAL COMPANY (US) 1984-03-20 US disclosed
US-4361708-A HEATING A PHENOL IN NITROBENZENE IN PRESENCE OF OXIDATIVE COUPLINGCATALYST THE DOW CHEMICAL COMPANY (US) 1982-11-30 US disclosed
US-4354048-A Copper chromite catalysts for oxidative coupling of phenols THE DOW CHEMICAL COMPANY (US) 1982-10-12 US disclosed
US-4354047-A Nickel catalysts for oxidative coupling of phenols THE DOW CHEMICAL COMPANY (US) 1982-10-12 US disclosed
US-4230596-A ELECTROOPTICS THOMSON-CSF (FR) 1980-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030166644-A1 Compounds and uses thereof for decreasing activity of hormone-sensitive lipase LIPE, PNLIP, LPL ESR1 1412/4885ESR2 683/4885KAT8 1894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.