SCHEMBL4558062

SCHEMBL4558062

C=CCC1(c2ccc(O)cc2)CCCC(CC=C)(c2ccc(O)cc2)C1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 4/20 0.41
ESR1 P03372 2/20 0.41
HSD11B1 P28845 1/20 0.32
SLC6A3 Q01959 6/20 0.32
SLC6A4 P31645 5/20 0.32
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
DPP4 P27487 1/20 0.31
SLC6A2 P23975 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL491176 0.88 ESR1 (0.50) ESR2ESR1HSD11B1SLC6A3SLC6A4
SCHEMBL3655905 0.77 ESR2 (0.37) ESR2ESR1NR1H2NR1H3
SCHEMBL6691411 0.71 SLC6A3 (0.41) HSD11B1SLC6A3SLC6A4DPP4SLC6A2
SCHEMBL18668717 0.71 DPP4 (0.57) SLC6A3SLC6A4DPP4SLC6A2MEN1
SCHEMBL8735345 0.70 ESR1 (0.59) ESR2ESR1HSD11B1SLC6A3SLC6A4
SCHEMBL251313 0.69 DPP4 (0.55) SLC6A3SLC6A4DPP4SLC6A2MEN1
SCHEMBL14692734 0.69 SLC6A3 (0.39) HSD11B1SLC6A3SLC6A4DPP4SLC6A2
SCHEMBL8706024 0.68 ESR2 (0.57) ESR2ESR1HSD11B1SLC6A3SLC6A4
SCHEMBL20577248 0.68 DPP4 (0.36) SLC6A3SLC6A4DPP4SLC6A2MEN1
SCHEMBL6691360 0.68 SLC6A3 (0.35) HSD11B1SLC6A3SLC6A4SLC6A2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5344999-A Monomers with high glass transition temperatures and with ductility GENERAL ELECTRIC COMPANY (US) 1994-09-06 US claimed
EP-0602874-A1 1,3-Bis(4-hydroxyphenyl)-1,3-dialkylcyclohexanes and polycarbonates prepared therefrom GENERAL ELECTRIC COMPANY (US) 1994-06-22 EP claimed
JP-6239783-A None JP disclosed
US-7638091-B2 Methods of sterilizing polycarbonate articles and methods of manufacture SABIC INNOVATIVE PLASTICS IP B. V. (NL) 2009-12-29 US disclosed
EP-1776145-B1 METHODS OF STERILIZING POLYCARBONATE ARTICLES SABIC INNOVATIVE PLASTICS IP (NL) 2009-03-11 EP disclosed
EP-1776145-A1 METHODS OF STERILIZING POLYCARBONATE ARTICLES GENERAL ELECTRIC COMPANY (a New York Corporation) (US) 2007-04-25 EP disclosed
US-7135538-B2 Transparent polycarbonate-polysiloxane copolymer blend, method for the preparation thereof, and article derived therefrom GENERAL ELECTRIC COMPANY (US) 2006-11-14 US disclosed
WO-2006085970-A1 METHODS OF STERILIZING POLYCARBONATE ARTICLES GENERAL ELECTRIC COMPANY (US) 2006-08-17 WO disclosed
US-20060002814-A1 Methods of sterilizing polycarbonate articles and methods of manufacture SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2006-01-05 US disclosed
US-20050101757-A1 Transparent polycarbonate-polysiloxane copolymer blend, method for the preparation thereof, and article derived therefrom SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2005-05-12 US disclosed
EP-0625521-B1 Bisphosphine oxide monomers and polycarbonates prepared therefrom GEN ELECTRIC (US) 1999-08-04 EP disclosed
US-5344999-A Monomers with high glass transition temperatures and with ductility GENERAL ELECTRIC COMPANY (US) 1994-09-06 US disclosed
JP-H06239783-A 1,3-BIS(4-HYDROXYPHENYL)-1,3-DIALKYLCYCLOHEXANE AND POLYCARBONATE PREPARED THEREFROM GENERAL ELECTRIC CO <GE> 1994-08-30 JP disclosed
EP-0602874-A1 1,3-Bis(4-hydroxyphenyl)-1,3-dialkylcyclohexanes and polycarbonates prepared therefrom GENERAL ELECTRIC COMPANY (US) 1994-06-22 EP disclosed
EP-0602874-A1 1,3-Bis(4-hydroxyphenyl)-1,3-dialkylcyclohexanes and polycarbonates prepared therefrom GENERAL ELECTRIC COMPANY (US) 1994-06-22 EP disclosed
EP-0602874-A1 1,3-Bis(4-hydroxyphenyl)-1,3-dialkylcyclohexanes and polycarbonates prepared therefrom GENERAL ELECTRIC COMPANY (US) 1994-06-22 EP disclosed
US-5312890-A High glass transition temperature, high impact resistance, flame retardancy GENERAL ELECTRIC COMPANY (US) 1994-05-17 US disclosed
US-5281688-A Polycarbonate from 1,3-bis(4-hydroxyphenyl)-1,3-dialkylcyclohexanes GENERAL ELECTRIC COMPANY (US) 1994-01-25 US disclosed
US-5281688-A Polycarbonate from 1,3-bis(4-hydroxyphenyl)-1,3-dialkylcyclohexanes GENERAL ELECTRIC COMPANY (US) 1994-01-25 US disclosed
US-5281688-A Polycarbonate from 1,3-bis(4-hydroxyphenyl)-1,3-dialkylcyclohexanes GENERAL ELECTRIC COMPANY (US) 1994-01-25 US disclosed