Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | ME3 | Q16798 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3529467 | 0.86 | NOTUM (0.64) | ALDH1A1CYP2C19SMN1; SMN2PKMNPSR1 | |
| Benzene SCHEMBL28217786 | 0.84 | NOTUM (0.62) | RORCALDH1A1CYP2C19SMN1; SMN2PKM | |
| Hydrochloric Acid SCHEMBL28060567 | 0.84 | NOTUM (0.62) | RORCALDH1A1CYP2C19SMN1; SMN2PKM | |
| SCHEMBL23583023 | 0.84 | ITGB3 (0.61) | RORCALDH1A1CYP2C19SMN1; SMN2NPSR1 | |
| Hydrochloric Acid SCHEMBL28217785 | 0.82 | SMN1; SMN2 (0.62) | RORCALDH1A1SMN1; SMN2PKMNPSR1 | |
| SCHEMBL28033420 | 0.81 | ALDH1A1 (0.64) | RORCALDH1A1SMN1; SMN2NPSR1NPC1 | |
| SCHEMBL5367392 | 0.79 | HTR2A (0.71) | ALDH1A1GAAPKMLTA4HHTR2A | |
| SCHEMBL77188 | 0.78 | GFER (0.53) | ALDH1A1SMN1; SMN2GAAPKMNPSR1 | |
| SCHEMBL27582090 | 0.78 | ALDH1A1 (0.54) | RORCALDH1A1CYP2C19SMN1; SMN2PKM | |
| SCHEMBL5369479 | 0.77 | POLB (0.78) | ALDH1A1CYP2C19SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096565-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2015-08-04 | — | — | US | disclosed |
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | METHYLGENE INC. (CA) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | HDAC1, HDAC11, HDAC3 | RORC 787/4885ALDH1A1 532/4885CYP2C19 782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.