Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | PRCP | P42785 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4560517 | 0.94 | SLC6A2 (0.54) | SLC6A2SLC6A4ALDH1A1TSHRGLA | |
| SCHEMBL4558508 | 0.92 | SLC6A2 (0.53) | SLC6A2SLC6A4ALDH1A1TSHRGLA | |
| SCHEMBL378658 | 0.85 | SLC6A4 (0.47) | SLC6A2SLC6A4ALDH1A1TSHRGLA | |
| SCHEMBL157791 | 0.81 | SLC6A4 (0.54) | SLC6A2SLC6A4OPRM1 | |
| Hydrochloric Acid SCHEMBL27797653 | 0.80 | SLC6A2 (0.55) | SLC6A2SLC6A4ALDH1A1OPRM1POLB | |
| SCHEMBL12497899 | 0.80 | AKR1C1 (0.48) | ALDH1A1TSHRMEN1KMT2AOPRM1 | |
| SCHEMBL2595399 | 0.79 | TSHR (0.62) | SLC6A2SLC6A4ALDH1A1TSHRGLA | |
| Hydrochloric Acid SCHEMBL2236360 | 0.79 | ALDH1A1 (0.58) | SLC6A2SLC6A4ALDH1A1TSHRGLA | |
| SCHEMBL378699 | 0.78 | OPRM1 (0.43) | SLC6A2SLC6A4TSHRMEN1KMT2A | |
| SCHEMBL1415853 | 0.76 | SLC6A4 (0.56) | SLC6A2SLC6A4ALDH1A1TSHRGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096565-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2015-08-04 | — | — | US | disclosed |
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | METHYLGENE INC. (CA) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | HDAC1, HDAC11, HDAC3 | SLC6A2 2953/4885SLC6A4 2834/4885ALDH1A1 532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.