Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | PRCP | P42785 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4560517 | 0.95 | SLC6A2 (0.54) | SLC6A2SLC6A4ALDH1A1TSHRAKR1C1 | |
| SCHEMBL4558685 | 0.92 | SLC6A2 (0.57) | SLC6A2SLC6A4ALDH1A1TSHRAKR1C1 | |
| SCHEMBL378658 | 0.81 | SLC6A4 (0.47) | SLC6A2SLC6A4ALDH1A1TSHRGLA | |
| SCHEMBL518233 | 0.81 | ALDH1A1 (0.53) | SLC6A2SLC6A4ALDH1A1TSHRGLA | |
| SCHEMBL4862025 | 0.81 | ALDH1A1 (0.53) | SLC6A2SLC6A4ALDH1A1TSHRGLA | |
| SCHEMBL15776154 | 0.78 | AKR1C1 (0.53) | SLC6A2SLC6A4ALDH1A1TSHRAKR1C1 | |
| SCHEMBL5538599 | 0.78 | ALDH1A1 (0.50) | SLC6A2SLC6A4ALDH1A1TSHRGLA | |
| SCHEMBL3518014 | 0.78 | AKR1C1 (0.61) | SLC6A2SLC6A4ALDH1A1TSHRAKR1C1 | |
| SCHEMBL6472114 | 0.77 | ALDH1A1 (0.49) | SLC6A2SLC6A4ALDH1A1TSHRGLA | |
| Hydrochloric Acid SCHEMBL6926710 | 0.77 | ALDH1A1 (0.49) | SLC6A2SLC6A4ALDH1A1TSHRGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096565-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2015-08-04 | — | — | US | disclosed |
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | METHYLGENE INC. (CA) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | HDAC1, HDAC11, HDAC3 | SLC6A2 2953/4885SLC6A4 2834/4885ALDH1A1 532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.