Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.62 |
| ▸ | MLYCD | O95822 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | KDM4A | O75164 | 1/20 | 0.52 |
| ▸ | KDM5A | P29375 | 1/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.52 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.52 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.52 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4558654 | 0.95 | MLYCD (0.58) | ALOX5MLYCDALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL4161430 | 0.89 | MLYCD (0.68) | ALOX5MLYCDALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL1114818 | 0.85 | ALDH1A1 (0.59) | MLYCDALDH1A1SMN1; SMN2GLATSHR | |
| SCHEMBL1114803 | 0.84 | ALDH1A1 (0.58) | MLYCDALDH1A1SMN1; SMN2GLATSHR | |
| SCHEMBL1115056 | 0.84 | ALDH1A1 (0.58) | MLYCDALDH1A1SMN1; SMN2GLATSHR | |
| SCHEMBL11518360 | 0.84 | TP53 (0.60) | ALDH1A1SMN1; SMN2GLATSHRTP53 | |
| SCHEMBL17439411 | 0.84 | TP53 (0.60) | ALDH1A1SMN1; SMN2GLATSHRTP53 | |
| SCHEMBL12679891 | 0.84 | ALDH1A1 (0.58) | MLYCDALDH1A1SMN1; SMN2HPGDGLA | |
| SCHEMBL17333743 | 0.83 | TP53 (0.64) | ALDH1A1SMN1; SMN2GLATSHRTP53 | |
| SCHEMBL12679904 | 0.83 | ALDH1A1 (0.56) | MLYCDALDH1A1SMN1; SMN2HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096565-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2015-08-04 | — | — | US | disclosed |
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | METHYLGENE INC. (CA) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | HDAC1, HDAC11, HDAC3 | ALOX5 2866/4885MLYCD 3261/4885ALDH1A1 532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.