Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4560617 | 0.98 | HCRTR1 (0.65) | HCRTR1HCRTR2 | |
| SCHEMBL4561085 | 0.90 | HCRTR1 (0.73) | HCRTR1HCRTR2 | |
| SCHEMBL4561832 | 0.88 | HCRTR1 (0.74) | HCRTR1HCRTR2 | |
| SCHEMBL4561847 | 0.87 | HCRTR1 (0.73) | HCRTR1HCRTR2 | |
| SCHEMBL4559459 | 0.87 | HCRTR1 (0.84) | HCRTR1HCRTR2 | |
| SCHEMBL4562085 | 0.79 | HCRTR1 (0.82) | HCRTR1HCRTR2 | |
| SCHEMBL4561940 | 0.78 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL9977828 | 0.74 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL4562391 | 0.72 | HCRTR1 (0.71) | HCRTR1HCRTR2 | |
| SCHEMBL15326973 | 0.69 | HCRTR1 (0.45) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011775-A1 | AMIDOETHYL ALKYLAMINO OREXIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2009-01-22 | — | — | WO | claimed |
| US-10894042-B2 | Methods and pharmaceutical compositions for the treatment of cancer | Inserm (Institut National de la Santa et de la Recherche Medicale) (FR) | 2021-01-19 | — | — | US | disclosed |
| US-20190151304-A1 | METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF AUTOIMMUNE INFLAMMATORY | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2019-05-23 | — | — | US | disclosed |
| US-20190083508-A1 | USE OF OX1R ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASES | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2019-03-21 | — | — | US | disclosed |
| WO-2009011775-A1 | AMIDOETHYL ALKYLAMINO OREXIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2009-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190151304-A1 | METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF AUTOIMMUNE INFLAMMATORY | HCRTR1, HCRTR2, OXTR | HCRTR1 1/4885HCRTR2 2/4885 |
| US-10894042-B2 | Methods and pharmaceutical compositions for the treatment of cancer | OXTR, OGFR, OXGR1 | HCRTR1 18/4885HCRTR2 14/4885 |
| US-20190083508-A1 | USE OF OX1R ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASES | GPR180, OXGR1, MLNR | HCRTR1 22/4885HCRTR2 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.