Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4559778 | 0.77 | CSF1R (0.36) | ALDH1A1GLAPTGESL3MBTL1KMT2A | |
| SCHEMBL18414587 | 0.65 | ALDH1A1 (0.41) | ALDH1A1GLAL3MBTL1KMT2AHTT | |
| SCHEMBL8297342 | 0.63 | — | — | |
| SCHEMBL16423006 | 0.61 | — | — | |
| SCHEMBL14279781 | 0.61 | ALDH1A1 (0.47) | ALDH1A1GLAKMT2AHTTMEN1 | |
| SCHEMBL3348546 | 0.60 | ALDH1A1 (0.50) | ALDH1A1GLAKMT2AHTTMEN1 | |
| SCHEMBL1663200 | 0.60 | CREBBP (0.54) | ALDH1A1GLAL3MBTL1KMT2AHTT | |
| SCHEMBL1160193 | 0.60 | MEN1 (0.50) | ALDH1A1GLAKMT2AHTTMEN1 | |
| SCHEMBL11327883 | 0.59 | ALDH1A1 (0.53) | ALDH1A1GLAKMT2AHTTMEN1 | |
| SCHEMBL28498547 | 0.59 | ALDH1A1 (0.53) | ALDH1A1GLAL3MBTL1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009094205-A2 | 3-ARYL-6-ARYL-7H-[1,2,4]TRIAZOLO[3,4-B][1,3,4]THIADIAZINES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2009-07-30 | — | — | WO | disclosed |