Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 6/20 | 0.36 |
| ▸ | HTR2B | P41595 | 6/20 | 0.36 |
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634708 | 0.79 | PRCP (0.38) | HTR2CHTR2BHTR2AHRH3SLC6A2 | |
| SCHEMBL4019122 | 0.77 | KDM1A (0.42) | KDM1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL874497 | 0.75 | HTR2A (0.34) | HTR2CHTR2A | |
| SCHEMBL455932 | 0.75 | HTR2A (0.34) | KDM1AHTR2CHTR2A | |
| SCHEMBL3669240 | 0.74 | KDM4E (0.30) | GAA | |
| SCHEMBL3389204 | 0.72 | HTR2A (0.35) | KDM1AHTR2CHTR2A | |
| SCHEMBL11116079 | 0.72 | TSHR (0.34) | HTR2CHTR2BHTR2AHRH3GAA | |
| SCHEMBL4307808 | 0.71 | HTR2A (0.34) | HTR2CHTR2A | |
| SCHEMBL4290508 | 0.71 | HTR2A (0.35) | HTR2CHTR2BHTR2A | |
| SCHEMBL458123 | 0.71 | HTR2A (0.34) | HTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941231-A1 | HETEROARYLIC-ARYLIC DIPHOSPHINES AS CHIRAL LIGANDS | CHEMI S.p.A. (IT) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998022484-A1 | HETEROARYLIC-ARYLIC DIPHOSPHINES AS CHIRAL LIGANDS | CHEMI S.P.A. (IT) | 1998-05-28 | — | — | WO | disclosed |