Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | CBLB | Q13191 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4560488 | 0.85 | EGLN1 (0.49) | EGLN1HDAC3HDAC1HDAC2USP30 | |
| SCHEMBL6368422 | 0.79 | PYGL (0.51) | EGLN1HDAC3HDAC1HDAC2MCHR1 | |
| SCHEMBL31016920 | 0.76 | HDAC3 (0.65) | EGLN1HDAC3HDAC1HDAC2EGFR | |
| SCHEMBL16307678 | 0.76 | HDAC3 (0.57) | EGLN1HDAC3HDAC1HDAC2USP30 | |
| SCHEMBL5926432 | 0.75 | MEN1 (0.60) | EGLN1CBLBMAP3K5EGFR | |
| SCHEMBL213288 | 0.74 | EGLN1 (0.60) | EGLN1HDAC3HDAC1HDAC2USP30 | |
| SCHEMBL14883271 | 0.74 | EGLN1 (0.56) | EGLN1HDAC3HDAC1HDAC2USP30 | |
| SCHEMBL27482350 | 0.72 | EGLN1 (0.46) | EGLN1HDAC3HDAC1HDAC2USP30 | |
| SCHEMBL14876092 | 0.72 | EGLN1 (0.57) | EGLN1HDAC3HDAC1HDAC2USP30 | |
| SCHEMBL14875993 | 0.71 | EGLN1 (0.57) | EGLN1HDAC3HDAC1HDAC2USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090238761-A1 | Novel Aryl Piperazine Derivatives With Medical Utility | UNIVERSITA DEGLI STUDI DI SIENA (IT) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090238761-A1 | Novel Aryl Piperazine Derivatives With Medical Utility | HTR2C, HTR2A, DRD2 | EGLN1 2852/4885HDAC3 868/4885HDAC1 2598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.