Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13359209 | 0.86 | DNM1 (0.31) | ALDH1A1EPHX1DNM1MEN1KMT2A | |
| SCHEMBL2328235 | 0.77 | CYP1A2 (0.34) | — | |
| SCHEMBL24569291 | 0.71 | SIGMAR1 (0.39) | ALDH1A1EPHX1DNM1MEN1KMT2A | |
| SCHEMBL22131106 | 0.71 | SIGMAR1 (0.39) | ALDH1A1EPHX1DNM1MEN1KMT2A | |
| SCHEMBL11040811 | 0.69 | ARG1 (0.32) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5200384 | 0.69 | — | — | |
| SCHEMBL5345418 | 0.68 | TDP1 (0.40) | ALDH1A1EPHX1 | |
| SCHEMBL5352300 | 0.68 | TDP1 (0.40) | ALDH1A1EPHX1 | |
| SCHEMBL9762479 | 0.68 | TDP1 (0.40) | ALDH1A1EPHX1 | |
| SCHEMBL10594449 | 0.68 | TDP1 (0.40) | ALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7501453-B2 | Cyclopropanes with central nervous system activity | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2009-03-10 | — | — | US | disclosed |
| US-20070244201-A1 | Cyclopropanes with central nervous system activity | NIH-DEITR | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244201-A1 | Cyclopropanes with central nervous system activity | PMP22, CNR1, CNR2 | ALDH1A1 1554/4885EPHX1 530/4885CYP3A4 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.