SCHEMBL456029

SCHEMBL456029

CCCCNC(O)(O)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.45
EPHX1 P07099 5/20 0.40
ACHE P22303 6/20 0.38
MMP2 P08253 1/20 0.38
AKR1B1 P15121 1/20 0.36
KDM4C Q9H3R0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL452902 0.86 KDM4C (0.42) ALOX15EPHX1MMP2KDM4C
SCHEMBL4542993 0.83
SCHEMBL28370224 0.77 KDM4C (0.48) ALOX15EPHX1ACHEMMP2AKR1B1
SCHEMBL453463 0.75
SCHEMBL28841674 0.74 EPHX1 (0.48) EPHX1
SCHEMBL28841688 0.74 EPHX1 (0.48) EPHX1
SCHEMBL28953131 0.74 EPHX1 (0.48) EPHX1
SCHEMBL28841687 0.74 EPHX1 (0.48) EPHX1
SCHEMBL31477734 0.74 ALOX15 (0.42) ALOX15EPHX1ACHEMMP2AKR1B1
SCHEMBL10547847 0.73 ALDH1A1 (0.36) KDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101421372-A Crosslinking compositions and methods of use thereof DU PONT (US) 2009-04-29 CN claimed
US-9126178-B2 Heat-expandable microspheres and a method of making heat-expandable microspheres and application thereof MATSUMOTO YUSHI-SEIYAKU CO., LTD. (JP) 2015-09-08 US disclosed
CN-101421373-B Zirconium crosslinking compositions and methods of use DU PONT 2013-04-10 CN disclosed
EP-2529830-A2 Heat-expandable microspheres and a method of making heat-expandable microspheres and application thereof MATSUMOTO YUSHI-SEIYAKU CO., LTD. (JP) 2012-12-05 EP disclosed
EP-2441814-A1 HEAT-EXPANDABLE MICROSPHERE, METHOD FOR PRODUCING SAME AND USE OF SAME Matsumoto Yushi-Seiyaku Co., Ltd. (JP) 2012-04-18 EP disclosed
US-20120064347-A1 HEAT-EXPANDABLE MICROSPHERES AND A METHOD OF MAKING HEAT-EXPANDABLE MICROSPHERES AND APPLICATION THEREOF MATSUMOTO YUSHI-SEIYAKU CO., LTD. (JP) 2012-03-15 US disclosed
CN-101421373-A Zirconium crosslinking compositions and methods of use DU PONT (US) 2009-04-29 CN disclosed
CN-101421372-A Crosslinking compositions and methods of use thereof DU PONT (US) 2009-04-29 CN disclosed
CN-100347230-C Water-base composition and crosslinking agent for water-soluble polymers MATSUMOTO CHEMICAL INDUSTRY CO (JP) 2007-11-07 CN disclosed
CN-1606606-A Water-base composition and crosslinking agent for water-soluble polymers MATSUMOTO CHEMICAL INDUSTRY CO (JP) 2005-04-13 CN disclosed