Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30202433 | 1.00 | ALDH1A1 (0.67) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL95129 | 0.89 | ALDH1A1 (0.56) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29428385 | 0.89 | ALDH1A1 (0.56) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5715031 | 0.87 | ALDH1A1 (0.52) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5809528 | 0.86 | ALDH1A1 (0.67) | ALDH1A1BCL2L1MCL1MAPTHTT | |
| SCHEMBL11113125 | 0.85 | ALDH1A1 (0.89) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL15933382 | 0.85 | ALDH1A1 (0.53) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL27494174 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6855890 | 0.82 | TUBB4A (0.47) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5715034 | 0.82 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1589 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1870084-B1 | Composition for dyeing keratin fibres comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, 6-chloro 2-methyl 5-aminophenol and a substituted meta-aminophenol | ORÉAL L (FR) | 2015-07-22 | — | — | EP | claimed |
| EP-1870085-B1 | Composition for dyeing keratinous fibres comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, para-phenylenediamine or para-toluenediamine and a substituted meta-aminophenol | ORÉAL L (FR) | 2015-07-22 | — | — | EP | claimed |
| EP-0850636-B2 | Composition for the oxidative dyeing of keratinic fibres and dyeing process using this composition | OREAL (FR) | 2013-11-20 | — | — | EP | claimed |
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | claimed |
| US-8043385-B2 | Composition oxidation colouring of keratinic fibres, containing a cationic cellulose ether, a metasilicate and oxidation dyes, method for oxidation colouring and uses thereof | L'OREAL S.A. (FR) | 2011-10-25 | — | — | US | claimed |
| JP-4785024-B2 | — | — | 2011-10-05 | — | — | JP | claimed |
| US-8002847-B2 | Composition for oxidation dyeing keratin fibres comprising a cationic cellulose ether, a weakly oxyethylenated sorbitan fatty acid ester and oxidation dyes | L 'OREAL S.A. (FR) | 2011-08-23 | — | — | US | claimed |
| US-20100275388-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | L'OREAL S.A. (FR) | 2010-11-04 | — | — | US | claimed |
| US-20100263138-A1 | COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF | L'OREAL S.A. (FR) | 2010-10-21 | — | — | US | claimed |
| EP-1494995-B1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | PROCTER & GAMBLE (US) | 2010-09-22 | — | — | EP | claimed |
| WO-1998023246-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBERS CONTAINING 2-FLUORO 4-AMINOPHENOL, A META-AMINOPHENOL AND/OR A META-PHENYLENEDIAMINE AND DYEING METHOD USING SUCH A COMPOSITION | L'OREAL (FR) | 1998-06-04 | — | — | WO | claimed |
| WO-1998017233-A1 | DYEING AGENT FOR DYEING KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 1998-04-30 | — | — | WO | claimed |
| CN-1178104-A | Compositions for oxidation dyeing of keratin fibres and dyeing process using them | OREAL (FR) | 1998-04-08 | — | — | CN | claimed |
| US-5735909-A | Compositions and processes for the oxidation dyeing of keratin fibres with an oxidation base, a meta-aminophenol coupler, and a 6-hydroxyindoline coupler | L'OREAL (FR) | 1998-04-07 | — | — | US | claimed |
| EP-0819424-A1 | Oxidative hair dye composition and the dyeing process using such a composition | L'OREAL (FR) | 1998-01-21 | — | — | EP | claimed |
| EP-0819423-A1 | Composition for the oxydative dyeing of keratinic fibers and dyeing process applying them | L'OREAL (FR) | 1998-01-21 | — | — | EP | claimed |
| WO-1997011674-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES, AND DYEING METHOD USING SAME | L'OREAL (FR) | 1997-04-03 | — | — | WO | claimed |
| EP-0728465-B1 | Composition for dyeing keratinous fibers comprising a meta-aminophenol and 6-hydroxyindoline, and dyeing process using such a composition | OREAL (FR) | 1997-03-19 | — | — | EP | claimed |
| EP-0728465-A1 | Composition for dyeing keratinous fibers comprising a meta-aminophenol and 6-hydroxyindoline, and dyeing process using such a composition | L'OREAL (FR) | 1996-08-28 | — | — | EP | claimed |
| CN-1109737-A | Composition forthe oxidation dyeingof keratinous fiberes comprising a para-phenylenediamine containinga primary, secondary or tertiary amine function, a meta-phenylenediamine and a para-aminopheno.... | OREAL (FR) | 1995-10-11 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100275388-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | KRT18, KRTCAP2, FASN | ALDH1A1 1792/4885CYP1A2 1251/4885CYP2D6 2085/4885 |
| US-20100263138-A1 | COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF | KRT18, TUBB3, VIM | ALDH1A1 1691/4885CYP1A2 814/4885CYP2D6 1259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.