Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9894331 | 0.84 | MAPT (0.56) | MAPTKDM4ETSHRMAPK1SMN1; SMN2 | |
| SCHEMBL27578928 | 0.84 | KDM4E (0.44) | MAPTKDM4EL3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL11768659 | 0.82 | KDM4E (0.50) | MAPTKDM4EL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL7960592 | 0.81 | SMN1; SMN2 (0.60) | MAPTKDM4EL3MBTL1TSHRMAPK1 | |
| SCHEMBL7959390 | 0.79 | KDM4E (0.55) | MAPTKDM4EL3MBTL1TSHRMAPK1 | |
| SCHEMBL7293735 | 0.78 | KDM4E (0.54) | MAPTKDM4EL3MBTL1TSHRMAPK1 | |
| SCHEMBL462187 | 0.77 | ALDH1A1 (0.46) | MAPTKDM4EMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6558284 | 0.77 | KDM4E (0.53) | MAPTKDM4EL3MBTL1TSHRMAPK1 | |
| SCHEMBL27457904 | 0.76 | DHODH (0.48) | MAPTKDM4EL3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL454709 | 0.75 | ALDH1A1 (0.44) | MAPTKDM4EL3MBTL1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2475654-A1 | HERBICIDAL PYRIMIDONE DERIVATIVES | E. I. du Pont de Nemours and Company (US) | 2012-07-18 | — | — | EP | disclosed |
| WO-2012033548-A2 | HERBICIDAL BIS-NITROGEN-CONTAINING OXO AND SULFONO HETEROCYCLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-15 | — | — | WO | disclosed |
| WO-2011031658-A1 | HERBICIDAL PYRIMIDONE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-17 | — | — | WO | disclosed |