Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 2/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11768659 | 0.78 | KDM4E (0.50) | ALDH1A1MAPTHTTRAB9ALMNA | |
| SCHEMBL456136 | 0.77 | MAPT (0.52) | ALDH1A1MAPTCHRM2CHRM4CHRM5 | |
| SCHEMBL9894423 | 0.75 | MAPT (0.54) | ALDH1A1MAPTRAB9ALMNAKDM4E | |
| SCHEMBL7960592 | 0.72 | SMN1; SMN2 (0.60) | ALDH1A1MAPTRAB9ALMNAKDM4E | |
| SCHEMBL454709 | 0.72 | ALDH1A1 (0.44) | ALDH1A1MAPTRAB9ALMNAKDM4E | |
| SCHEMBL9894331 | 0.71 | MAPT (0.56) | ALDH1A1MAPTRAB9ALMNAKDM4E | |
| SCHEMBL7959390 | 0.70 | KDM4E (0.55) | ALDH1A1MAPTRAB9ALMNAKDM4E | |
| SCHEMBL7293735 | 0.70 | KDM4E (0.54) | ALDH1A1MAPTHTTRAB9ALMNA | |
| SCHEMBL4597811 | 0.69 | TSHR (0.64) | ALDH1A1MAPTRAB9ATDP1SMN1; SMN2 | |
| SCHEMBL12929472 | 0.69 | ALDH1A1 (0.63) | ALDH1A1MAPTCHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2475654-A1 | HERBICIDAL PYRIMIDONE DERIVATIVES | E. I. du Pont de Nemours and Company (US) | 2012-07-18 | — | — | EP | disclosed |
| WO-2012033548-A2 | HERBICIDAL BIS-NITROGEN-CONTAINING OXO AND SULFONO HETEROCYCLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-15 | — | — | WO | disclosed |
| WO-2011031658-A1 | HERBICIDAL PYRIMIDONE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-17 | — | — | WO | disclosed |