Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9894331 | 0.86 | MAPT (0.56) | SMN1; SMN2ALDH1A1HPGDTSHRMAPT | |
| SCHEMBL31558583 | 0.86 | KDM4E (0.51) | SMN1; SMN2ALDH1A1HPGDTSHRMAPT | |
| SCHEMBL7959390 | 0.85 | KDM4E (0.55) | SMN1; SMN2ALDH1A1HPGDTSHRMAPT | |
| SCHEMBL7293735 | 0.84 | KDM4E (0.54) | SMN1; SMN2ALDH1A1HPGDTSHRMAPT | |
| SCHEMBL6558284 | 0.83 | KDM4E (0.53) | SMN1; SMN2ALDH1A1HPGDTSHRMAPT | |
| SCHEMBL1527905 | 0.81 | MAPT (0.58) | SMN1; SMN2ALDH1A1HPGDTSHRMAPT | |
| SCHEMBL456136 | 0.81 | MAPT (0.52) | SMN1; SMN2ALDH1A1HPGDTSHRMAPT | |
| SCHEMBL30765677 | 0.77 | KDM4E (0.49) | ALDH1A1HPGDKDM4ECYP1A2CYP2C9 | |
| SCHEMBL7965688 | 0.77 | KDM4E (0.45) | SMN1; SMN2ALDH1A1HPGDTSHRKDM4E | |
| SCHEMBL7951054 | 0.77 | CYP1A2 (0.43) | SMN1; SMN2ALDH1A1HPGDTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300337-B1 | Acetamide derivative and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-1055683-A1 | NOVEL ACETAMIDE DERIVATIVE AND USE THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-11-29 | — | — | EP | disclosed |