Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 15/20 | 0.57 |
| ▸ | DAO | P14920 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6448492 | 0.86 | RHEB (0.56) | RHEBDAOFLT3HRH4 | |
| SCHEMBL4979042 | 0.85 | DAO (0.51) | RHEBDAOFLT3HRH4 | |
| SCHEMBL19013674 | 0.83 | DAO (0.50) | RHEBDAOFLT3HRH4 | |
| SCHEMBL5917425 | 0.81 | DAO (0.49) | RHEBDAOFLT3HRH4 | |
| SCHEMBL28189726 | 0.81 | DAO (0.49) | RHEBDAOFLT3HRH4 | |
| SCHEMBL20536135 | 0.81 | RHEB (0.76) | RHEB | |
| SCHEMBL1439650 | 0.80 | DAO (0.51) | RHEBDAOFLT3HRH4 | |
| SCHEMBL30468720 | 0.80 | DAO (0.51) | RHEBDAOFLT3HRH4 | |
| SCHEMBL5768535 | 0.79 | RHEB (0.51) | RHEBDAOHRH4 | |
| SCHEMBL12490200 | 0.79 | RHEB (0.51) | RHEBDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065062-A1 | NOVEL ANTIVIRAL COMPOUNDS | PHARMARESOURCES(SHANGHAI)CO., LTD. (CN) | 2012-05-18 | — | — | WO | disclosed |
| US-3996241-A | 2-Hydroxymethyl indole compounds and blood sugar lowering compositions | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1976-12-07 | — | — | US | disclosed |