Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.51 |
| ▸ | PCSK9 | Q8NBP7 | 3/20 | 0.47 |
| ▸ | RHEB | Q15382 | 5/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19013674 | 0.86 | DAO (0.50) | DAOPCSK9RHEBNOS1FLT3 | |
| SCHEMBL6448492 | 0.85 | RHEB (0.56) | DAORHEBNOS1FLT3HRH4 | |
| SCHEMBL28189726 | 0.85 | DAO (0.49) | DAOPCSK9RHEBNOS1FLT3 | |
| SCHEMBL5917425 | 0.85 | DAO (0.49) | DAOPCSK9RHEBNOS1FLT3 | |
| SCHEMBL4561870 | 0.85 | RHEB (0.57) | DAORHEBFLT3HRH4 | |
| SCHEMBL7495171 | 0.84 | DAO (0.45) | DAOPCSK9RHEBFLT3 | |
| SCHEMBL30468720 | 0.79 | DAO (0.51) | DAORHEBFLT3HRH4 | |
| SCHEMBL1439650 | 0.79 | DAO (0.51) | DAORHEBFLT3HRH4 | |
| SCHEMBL27524233 | 0.78 | DAO (0.43) | DAORHEBFLT3HRH4GPR84 | |
| SCHEMBL19014121 | 0.77 | DAO (0.42) | DAOPCSK9RHEBNOS1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236848-B2 | Along with a concentrate of Aloe Vera and a carrier; suspension as microparticles in a starch carrier matrix; including an immunopotentiating steroid; to treat warts and human papilloma virus (HPV) related conditions of the oropharynx, larynx, genitalia, and uterine cervix; oral, topical administration | BIORESPONSE, L.L.C. (US) | 2012-08-07 | — | — | US | disclosed |
| US-20080145418-A1 | Diindolylmethane for the treatment of HPV infection | BIORESPONSE L.L.C., | 2008-06-19 | — | — | US | disclosed |
| US-7348352-B2 | Diindolylmethane for the treatment of HPV infection | BIORESPONSE L.L.C. (US) | 2008-03-25 | — | — | US | disclosed |
| US-20030096855-A1 | Diindolylmethane for the treatment of HPV infection | BIORESPONSE L.L.C. | 2003-05-22 | — | — | US | disclosed |