Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SI | P14410 | 2/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128775 | 0.81 | LMNA (0.41) | NPC1RAB9A | |
| SCHEMBL14771418 | 0.77 | MGAM (0.38) | MGAMGAASIMGAM2 | |
| SCHEMBL10027329 | 0.77 | ADORA3 (0.52) | — | |
| SCHEMBL5924180 | 0.74 | CSNK2A2 (0.42) | — | |
| SCHEMBL3109602 | 0.71 | MGAM (0.60) | NPC1RAB9AMGAMGAASI | |
| SCHEMBL22761577 | 0.71 | ADORA3 (0.38) | — | |
| SCHEMBL30166984 | 0.71 | MGAM (0.60) | NPC1RAB9AMGAMGAASI | |
| SCHEMBL3711999 | 0.71 | DAO (0.37) | NPC1RAB9AGAA | |
| SCHEMBL6139156 | 0.71 | PARP1 (0.41) | NPC1RAB9AMGAMGAASI | |
| SCHEMBL1192237 | 0.71 | NPC1 (0.50) | NPC1RAB9AMGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065062-A1 | NOVEL ANTIVIRAL COMPOUNDS | PHARMARESOURCES(SHANGHAI)CO., LTD. (CN) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012065062-A1 | NOVEL ANTIVIRAL COMPOUNDS | PHARMARESOURCES(SHANGHAI)CO., LTD. (CN) | 2012-05-18 | — | — | WO | disclosed |