⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666337 | 0.90 | ADH1B (0.37) | — | |
| SCHEMBL1451000 | 0.90 | — | — | |
| SCHEMBL28322845 | 0.89 | CHRM2 (0.30) | — | |
| SCHEMBL5543967 | 0.88 | ADH1B (0.40) | — | |
| SCHEMBL73403 | 0.88 | ADH1B (0.40) | — | |
| SCHEMBL27705383 | 0.88 | ADH1B (0.40) | — | |
| SCHEMBL5546608 | 0.85 | — | — | |
| SCHEMBL1978098 | 0.84 | DAO (0.33) | — | |
| SCHEMBL27367584 | 0.84 | GABRA5 (0.35) | — | |
| SCHEMBL4622381 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-A | N- (pyridine -2- base) pyridine-sulfamide derivative and its purposes for disease treatment | 诺华股份有限公司 | 2019-04-16 | — | — | CN | claimed |
| EP-2758051-B1 | CYANOMETHYLPYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2018-04-11 | — | — | EP | claimed |
| EP-2758389-B1 | PYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2017-06-07 | — | — | EP | claimed |
| US-9394282-B2 | Pyrazole carboxamides as Janus kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-07-19 | — | — | US | claimed |
| US-9328099-B2 | Cyanomethylpyrazole carboxamides as janus kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-05-03 | — | — | US | claimed |
| US-20140235641-A1 | PYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS | INTERVET INC. | 2014-08-21 | — | — | US | claimed |
| US-20140228348-A1 | CYANOMETHYLPYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME LLC | 2014-08-14 | — | — | US | claimed |
| US-4269773-A | CEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1981-05-26 | — | — | US | claimed |
| US-4092474-A | Cephalosporins having a metaloxy group in 3-substituent | SHIONOGI & CO., LTD. (JA) | 1978-05-30 | — | — | US | claimed |
| EP-4029856-B1 | ARYLAZOLE COMPOUND AND PEST CONTROL AGENT | NIPPON SODA CO (JP) | 2024-03-27 | — | — | EP | disclosed |
| US-11884633-B2 | Arylazole compound and pest control agent | NIPPON SODA CO., LTD. (JP) | 2024-01-30 | — | — | US | disclosed |
| CN-115181067-A | Arylpyrazole compound and pest control agent | 日本曹达株式会社 | 2022-10-14 | — | — | CN | disclosed |
| EP-4029856-A1 | ARYLAZOLE COMPOUND AND PEST CONTROL AGENT | Nippon Soda Co., Ltd. (JP) | 2022-07-20 | — | — | EP | disclosed |
| CN-108430976-B | Arylpyrazole compound and pest control agent | 日本曹达株式会社 | 2022-07-05 | — | — | CN | disclosed |
| US-4269773-A | CEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1981-05-26 | — | — | US | disclosed |
| US-4183928-A | Haloarylmalonamidooxacephalosporins | SHIONOGI AND CO., LTD. (JP) | 1980-01-15 | — | — | US | disclosed |
| US-4160085-A | Cyclization to form cephem ring and intermediates therefor | SHIONOGI & CO., LTD. (JP) | 1979-07-03 | — | — | US | disclosed |
| US-4159984-A | METAL AND PROTON DONOR | SHIONOGI & CO., LTD. (JP) | 1979-07-03 | — | — | US | disclosed |
| US-4092474-A | Cephalosporins having a metaloxy group in 3-substituent | SHIONOGI & CO., LTD. (JA) | 1978-05-30 | — | — | US | disclosed |
| US-4079181-A | INTERMEDIATES FOR 3-HYDROXY-3-CEPHEM COMPOUNDS | SHIONOGI & CO., LTD. (JA) | 1978-03-14 | — | — | US | disclosed |