Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | HTR1F | P30939 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29686864 | 0.88 | HTR6 (0.68) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL5746143 | 0.88 | HTR6 (0.68) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL30949526 | 0.87 | HTR6 (0.59) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL11218072 | 0.87 | HTR6 (0.59) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL3622907 | 0.83 | HTR6 (0.64) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL3614305 | 0.81 | HTR6 (0.54) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL4384956 | 0.80 | HTR6 (0.53) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL3613863 | 0.80 | HTR6 (0.53) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL27993631 | 0.80 | FABP4 (0.60) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL3622449 | 0.77 | HTR6 (0.65) | HTR6HTR1AHTR1DHTR1BHTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034581-A1 | SUBSTITUTED INDOLYL COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2009-03-19 | — | — | WO | disclosed |