Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 17/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR1F | P30939 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3241536 | 0.89 | HTR6 (0.61) | HTR6HTR2AMEN1KMT2AMET | |
| SCHEMBL29687030 | 0.89 | HTR6 (0.61) | HTR6HTR2AMEN1KMT2AMET | |
| SCHEMBL30958262 | 0.86 | HTR6 (0.53) | HTR6HTR2AMEN1KMT2AALDH3A1 | |
| SCHEMBL11244064 | 0.86 | HTR6 (0.53) | HTR6HTR2AMEN1KMT2AALDH3A1 | |
| SCHEMBL4562485 | 0.80 | HTR6 (0.59) | HTR6MEN1KMT2AALDH3A1HTR1A | |
| SCHEMBL3614305 | 0.77 | HTR6 (0.54) | HTR6MEN1KMT2AALDH3A1HTR1A | |
| SCHEMBL5698343 | 0.76 | MET (0.53) | HTR6HTR2AMEN1KMT2AMET | |
| SCHEMBL3613863 | 0.76 | HTR6 (0.53) | HTR6MEN1KMT2AALDH3A1HTR1A | |
| SCHEMBL27993631 | 0.76 | FABP4 (0.60) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL3622907 | 0.76 | HTR6 (0.64) | HTR6HTR1AHTR1DHTR1BHTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034581-A1 | SUBSTITUTED INDOLYL COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2009-03-19 | — | — | WO | disclosed |