Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.62 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.62 |
| ▸ | HTR6 | P50406 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060858 | 0.84 | NOD1 (0.59) | NOD1CXCL8HTR6L3MBTL1POLB | |
| SCHEMBL30558134 | 0.81 | NOD1 (0.53) | NOD1CXCL8HTR6L3MBTL1POLB | |
| SCHEMBL14502515 | 0.81 | NOD1 (0.53) | NOD1CXCL8HTR6L3MBTL1POLB | |
| SCHEMBL4065867 | 0.81 | NOD1 (0.62) | NOD1CXCL8HTR6CA12CA2 | |
| SCHEMBL13114468 | 0.80 | CCR2 (0.64) | NOD1CXCL8HTR6L3MBTL1POLB | |
| SCHEMBL10767782 | 0.79 | NOD1 (0.62) | NOD1CXCL8HTR6L3MBTL1POLB | |
| SCHEMBL28523374 | 0.78 | CA12 (0.60) | NOD1CXCL8HTR6L3MBTL1POLB | |
| SCHEMBL6867482 | 0.75 | RECQL (0.58) | NOD1CXCL8HTR6L3MBTL1POLB | |
| SCHEMBL6860277 | 0.75 | RECQL (0.58) | NOD1CXCL8HTR6L3MBTL1POLB | |
| SCHEMBL13767757 | 0.74 | NOD1 (0.46) | NOD1CXCL8HTR6L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034581-A1 | SUBSTITUTED INDOLYL COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2009-03-19 | — | — | WO | claimed |