Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 10/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 4/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 5/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060858 | 0.84 | NOD1 (0.59) | NOD1CA12CA2CA9HTR6 | |
| SCHEMBL4562545 | 0.81 | NOD1 (0.62) | NOD1CA12CA2CA9HTR6 | |
| SCHEMBL10199579 | 0.78 | RECQL (0.58) | NOD1CA12CA2CA9HTR6 | |
| SCHEMBL28417120 | 0.76 | NOD1 (0.55) | NOD1CA12CA2CA9NOD2 | |
| SCHEMBL6924345 | 0.74 | HTR6 (0.59) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL6924887 | 0.73 | ALOX5 (0.52) | NOD1HTR6NOD2GAACCR2 | |
| SCHEMBL8829927 | 0.71 | NOD1 (0.56) | NOD1CA12CA2CA9NOD2 | |
| SCHEMBL27733700 | 0.70 | RECQL (0.56) | NOD1CA12CA2CA9HTR6 | |
| SCHEMBL13542609 | 0.70 | CNR2 (0.73) | NOD1 | |
| SCHEMBL4059044 | 0.70 | TP53 (0.53) | NOD1CA2HTR6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034581-A1 | SUBSTITUTED INDOLYL COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2009-03-19 | — | — | WO | claimed |
| WO-2009034581-A1 | SUBSTITUTED INDOLYL COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2009-03-19 | — | — | WO | disclosed |