Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.35 |
| ▸ | TUBB | P07437 | 3/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4240634 | 0.81 | MAPT (0.39) | MEN1KMT2AMAPTDUSP3PTPN5 | |
| SCHEMBL13907796 | 0.80 | KMT2A (0.40) | MEN1KMT2AMAPTDUSP3PTPN5 | |
| SCHEMBL13907991 | 0.77 | MEN1 (0.41) | MEN1KMT2AMAPTDUSP3PTPN5 | |
| SCHEMBL4240777 | 0.74 | CYP2D6 (0.38) | MAPTLMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3960703 | 0.70 | MEN1 (0.40) | MEN1KMT2AMAPTDUSP3PTPN5 | |
| SCHEMBL11783128 | 0.66 | ALDH1A1 (0.48) | MEN1KMT2AMAPTL3MBTL1LMNA | |
| SCHEMBL1542506 | 0.66 | MAPT (0.37) | MEN1KMT2AMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL1542153 | 0.66 | MAPT (0.35) | MEN1KMT2AMAPTL3MBTL1LMNA | |
| SCHEMBL13907798 | 0.65 | MEN1 (0.39) | MEN1KMT2AMAPTDUSP3PTPN5 | |
| SCHEMBL11782179 | 0.65 | FABP6 (0.50) | MEN1KMT2AMAPTDUSP3PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034029-A2 | 1-SUBSTITUTED 4-HETEROCYCLYLPIPERIDINES FOR USE AS CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-03-19 | — | — | WO | disclosed |