Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.33 |
| ▸ | TUBB | P07437 | 2/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.33 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.33 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960703 | 0.89 | MEN1 (0.40) | MAPTKMT2AMEN1DUSP3PTPN5 | |
| SCHEMBL4562585 | 0.81 | MEN1 (0.38) | MAPTKMT2AMEN1DUSP3PTPN5 | |
| SCHEMBL3963475 | 0.81 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL3960529 | 0.75 | PARP1 (0.42) | MAPTLMNA | |
| SCHEMBL3962137 | 0.67 | DHODH (0.43) | SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL1542153 | 0.67 | MAPT (0.35) | MAPTKMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL1542506 | 0.67 | MAPT (0.37) | MAPTKMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11784591 | 0.65 | CBFB (0.44) | MAPTKMT2AMEN1DUSP3PTPN5 | |
| SCHEMBL9237989 | 0.63 | KMT2A (0.42) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL13907796 | 0.63 | KMT2A (0.40) | MAPTKMT2AMEN1DUSP3PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034029-A2 | 1-SUBSTITUTED 4-HETEROCYCLYLPIPERIDINES FOR USE AS CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-03-19 | — | — | WO | disclosed |