Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5067510 | 0.80 | — | — | |
| SCHEMBL5027626 | 0.77 | HSD11B1 (0.36) | HSD11B1 | |
| SCHEMBL3551350 | 0.77 | HSD11B1 (0.41) | HSD11B1 | |
| SCHEMBL30635290 | 0.76 | HSD11B1 (0.46) | HSD11B1 | |
| SCHEMBL5031157 | 0.75 | HSD11B1 (0.42) | HSD11B1 | |
| SCHEMBL28543459 | 0.73 | MEN1 (0.43) | HSD11B1 | |
| SCHEMBL7176021 | 0.73 | MEN1 (0.43) | HSD11B1 | |
| SCHEMBL5031121 | 0.72 | GAA (0.47) | — | |
| SCHEMBL27606473 | 0.64 | — | — | |
| SCHEMBL790002 | 0.63 | CYP2D6 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079727-A2 | KINASE INHIBITOR COMPOUNDS | Xcovery, INC. (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008033562-A2 | KINASE INHIBITOR COMPOUNDS | XCOVERY, INC. (US) | 2008-03-20 | — | — | WO | disclosed |