Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 10/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3551350 | 0.98 | HSD11B1 (0.41) | HSD11B1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28543459 | 0.94 | MEN1 (0.43) | HSD11B1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7176021 | 0.94 | MEN1 (0.43) | HSD11B1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5027626 | 0.93 | HSD11B1 (0.36) | HSD11B1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30635290 | 0.79 | HSD11B1 (0.46) | HSD11B1MEN1KMT2ALMNA | |
| SCHEMBL5031121 | 0.79 | GAA (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL28546286 | 0.75 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL4562587 | 0.75 | RBP4 (0.31) | HSD11B1 | |
| SCHEMBL22725318 | 0.74 | MEN1 (0.40) | HSD11B1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5031162 | 0.73 | HSD11B1 (0.45) | HSD11B1ALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429609-B2 | Pyrazole compound and medicinal composition containing the same | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2008-09-30 | — | — | US | disclosed |
| EP-1510516-A1 | PYRAZOLE COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2005-03-02 | — | — | EP | disclosed |