Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL89640 | 0.98 | — | — | |
| SCHEMBL4959149 | 0.90 | — | — | |
| SCHEMBL9214182 | 0.81 | TSHR (0.76) | TSHRALDH1A1THRBMEN1KMT2A | |
| SCHEMBL7369789 | 0.80 | TSHR (0.38) | TSHRALDH1A1MEN1KMT2ANAAA | |
| SCHEMBL2943905 | 0.79 | — | — | |
| SCHEMBL277225 | 0.79 | TSHR (0.61) | TSHRALDH1A1THRBMEN1KMT2A | |
| SCHEMBL107940 | 0.79 | TSHR (0.61) | TSHRALDH1A1THRBMEN1KMT2A | |
| SCHEMBL9206028 | 0.79 | TSHR (0.61) | TSHRALDH1A1THRBMEN1KMT2A | |
| SCHEMBL4399689 | 0.79 | TSHR (0.61) | TSHRALDH1A1THRBMEN1KMT2A | |
| SCHEMBL7697182 | 0.79 | TSHR (0.61) | TSHRALDH1A1THRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514404-B2 | PNA-neamine conjugates and methods for producing and using the same | UNIVERSITY OF MEDICINE & DENTISTRY OF NEW JERSEY (US) | 2009-04-07 | — | — | US | disclosed |
| US-20070225239-A1 | Pna-Neamine Conjugates and Methods for Producing and Using the Same | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225239-A1 | Pna-Neamine Conjugates and Methods for Producing and Using the Same | NCL, PNMT, RNMT | TSHR 1625/4885ALDH1A1 3716/4885THRB 2796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.