Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5004291 | 0.78 | PTGS2 (0.32) | — | |
| SCHEMBL18644923 | 0.74 | FAAH (0.33) | BRD4 | |
| SCHEMBL2115938 | 0.73 | KDM4E (0.36) | — | |
| SCHEMBL12249891 | 0.64 | BRD4 (0.30) | BRD4 | |
| SCHEMBL23201571 | 0.64 | BRD4 (0.41) | BRD4 | |
| SCHEMBL2423222 | 0.63 | DPP4 (0.38) | — | |
| SCHEMBL12249866 | 0.62 | — | — | |
| SCHEMBL19869613 | 0.62 | BRD4 (0.33) | BRD4 | |
| SCHEMBL12249893 | 0.61 | CYP11B2 (0.32) | — | |
| SCHEMBL2118349 | 0.61 | APP (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134688-A1 | FLUORINATED DERIVATIVES OF DEFERIPRONE | Apotex Technologies Inc. (CA) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008116301-A1 | FLUORINATED DERIVATIVES OF DEFERIPRONE | APOTEX TECHNOLOGIES INC. (CA) | 2008-10-02 | — | — | WO | disclosed |