Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 9/20 | 0.38 |
| ▸ | CTSS | P25774 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 3/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15695520 | 0.74 | KDM4E (0.41) | CTSKCTSSSYKALDH1A1L3MBTL1 | |
| SCHEMBL1233941 | 0.72 | ALDH1A1 (0.43) | AAK1KMT2ASYKMEN1ALDH1A1 | |
| SCHEMBL31146134 | 0.72 | KMT2A (0.49) | AAK1CTSKCTSSKMT2ATSHR | |
| SCHEMBL19403329 | 0.67 | KMT2A (0.40) | AAK1CTSKCTSSKMT2ATSHR | |
| SCHEMBL19403330 | 0.67 | KMT2A (0.40) | AAK1CTSKCTSSKMT2ATSHR | |
| SCHEMBL31145916 | 0.67 | KMT2A (0.49) | CTSKCTSSKMT2ATSHRHSD17B10 | |
| SCHEMBL1164017 | 0.66 | CTSK (0.53) | CTSKCTSSCTSBCTSL | |
| SCHEMBL2563210 | 0.66 | CTSK (0.53) | CTSKCTSSCTSBCTSL | |
| SCHEMBL1164016 | 0.66 | CTSK (0.53) | CTSKCTSSCTSBCTSL | |
| SCHEMBL29529110 | 0.65 | CTSS (0.43) | CTSKCTSSCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696912-A4 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2009-06-03 | — | — | EP | disclosed |
| EP-1696912-A2 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M Innovative Properties Company (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005079195-A2 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-09-01 | — | — | WO | disclosed |