Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456361 | 1.00 | ALDH1A1 (0.48) | ALDH1A1ALOX15TDP1TSHRRECQL | |
| SCHEMBL18531566 | 0.97 | ALDH1A1 (0.44) | ALDH1A1ALOX15TDP1TSHRRECQL | |
| SCHEMBL1071946 | 0.97 | ALDH1A1 (0.44) | ALDH1A1ALOX15TDP1TSHRRECQL | |
| SCHEMBL1071948 | 0.97 | ALDH1A1 (0.44) | ALDH1A1ALOX15TDP1TSHRRECQL | |
| SCHEMBL12216264 | 0.97 | ALDH1A1 (0.44) | ALDH1A1ALOX15TDP1TSHRRECQL | |
| SCHEMBL13885810 | 0.90 | ALDH1A1 (0.52) | ALDH1A1ALOX15TDP1TSHRRECQL | |
| SCHEMBL5873700 | 0.85 | ALDH1A1 (0.48) | ALDH1A1ALOX15TDP1TSHRRECQL | |
| SCHEMBL5873701 | 0.85 | ALDH1A1 (0.48) | ALDH1A1ALOX15TDP1TSHRRECQL | |
| SCHEMBL4623531 | 0.84 | ALDH1A1 (0.56) | ALDH1A1ALOX15TDP1TSHRRECQL | |
| SCHEMBL4286077 | 0.84 | ALDH1A1 (0.56) | ALDH1A1ALOX15TDP1TSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362281-A1 | MUTANT NQ-RHODOPSIN KR 2 | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2017-12-21 | — | — | US | claimed |
| EP-3237443-A1 | MUTANT NQ-RHODOPSIN KR 2 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2017-11-01 | — | — | EP | claimed |
| WO-2016102677-A1 | MUTANT NQ-RHODOPSIN KR 2 | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2016-06-30 | — | — | WO | claimed |
| EP-2614079-B1 | MUTANT CHANNELRHODOPSIN 2 | MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V (DE) | 2015-07-15 | — | — | EP | claimed |
| US-8748578-B2 | Mutant channelrhodopsin 2 | Max-Planck-Gesellschaft zur Foerderrung der Wissenschaften e.V. (DE) | 2014-06-10 | — | — | US | claimed |
| EP-2055714-B1 | Biological photo-receptors as directly light-controlled ion channels and their use | MAX PLANCK GESELLSCHAFT (DE) | 2014-05-07 | — | — | EP | claimed |
| US-8647870-B2 | Use of biological photoreceptors as directly light-activated ion channels | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2014-02-11 | — | — | US | claimed |
| US-20130281379-A1 | MUTANT CHANNELRHODOPSIN 2 | Max-Planck-Gesellschaft zur Foerderung der Wissenschaftern e.V. (DE) | 2013-10-24 | — | — | US | claimed |
| EP-2614079-A1 | MUTANT CHANNELRHODOPSIN 2 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-07-17 | — | — | EP | claimed |
| US-20130017597-A1 | USE OF BIOLOGICAL PHOTORECEPTORS AS DIRECTLY LIGHT-ACTIVATED ION CHANNELS | MAX-PLANCK-GESEL. ZUR FOERDERUNG DER WISSEN. EV. (DE) | 2013-01-17 | — | — | US | claimed |
| US-8202699-B2 | Use of biological photoreceptors as directly light-activated ion channels | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2012-06-19 | — | — | US | claimed |
| WO-2012032103-A1 | MUTANT CHANNELRHODOPSIN 2 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2012-03-15 | — | — | WO | claimed |
| US-20110086421-A1 | USE OF BIOLOGICAL PHOTORECEPTORS AS DIRECTLY LIGHT-ACTIVATED ION CHANNELS | MAX-PLANCK-GESEL.ZUR FOERDERUNG DER WISSEN. E.V. (DE) | 2011-04-14 | — | — | US | claimed |
| US-7824869-B2 | Use of biological photoreceptors as directly light-activated ion channels | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2010-11-02 | — | — | US | claimed |
| EP-2112510-A1 | Use of biological photo-receptors as direct light-controlled ion channels | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2009-10-28 | — | — | EP | claimed |
| EP-2055714-A2 | Biological photo-receptors as directly light-controlled ion channels and their use | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2009-05-06 | — | — | EP | claimed |
| EP-1492881-B1 | USE OF BIOLOGICAL PHOTORECEPTORS AS DIRECTLY LIGHT-ACTIVATED ION CHANNELS | MAX PLANCK GESELLSCHAFT (DE) | 2008-10-22 | — | — | EP | claimed |
| US-20050202398-A1 | Use of biological photoreceptors as directly light-activated ion channels | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2005-09-15 | — | — | US | claimed |
| EP-1492881-A2 | USE OF BIOLOGICAL PHOTORECEPTORS AS DIRECTLY LIGHT-ACTIVATED ION CHANNELS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2005-01-05 | — | — | EP | claimed |
| WO-2003084994-A2 | USE OF BIOLOGICAL PHOTORECEPTORS AS DIRECTLY LIGHT-ACTIVATED ION CHANNELS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2003-10-16 | — | — | WO | claimed |