Sugi Predict

Sugi Predict / Compounds / SCHEMBL4286077

SCHEMBL4286077

SCHEMBL4286077

CC(C)=C/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C=C(C)C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.56
▸ ALOX15 P16050 3/20 0.56
▸ TDP1 Q9NUW8 2/20 0.56
▸ RECQL P46063 2/20 0.56
▸ HSD17B10 Q99714 2/20 0.56
▸ TSHR P16473 2/20 0.56
▸ PTGS1 P23219 2/20 0.54
▸ LMNA P02545 3/20 0.52
▸ NR1I2 O75469 1/20 0.52
▸ PGR P06401 1/20 0.52
▸ MAPT P10636 4/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ DRD3 P35462 1/20 0.36
▸ SLCO1B3 Q9NPD5 1/20 0.36
▸ SLCO1B1 Q9Y6L6 1/20 0.36
▸ HIF1A Q16665 1/20 0.36
▸ GMNN O75496 1/20 0.36
▸ APEX1 P27695 1/20 0.36
▸ PMP22 Q01453 1/20 0.36
▸ PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17241564 1.00 ALDH1A1 (0.56) ALDH1A1ALOX15TDP1RECQLHSD17B10
SCHEMBL8679515 1.00 ALDH1A1 (0.56) ALDH1A1ALOX15TDP1RECQLHSD17B10
SCHEMBL2832568 1.00 ALDH1A1 (0.56) ALDH1A1ALOX15TDP1RECQLHSD17B10
SCHEMBL29470882 1.00 ALDH1A1 (0.56) ALDH1A1ALOX15TDP1RECQLHSD17B10
SCHEMBL4623531 1.00 ALDH1A1 (0.56) ALDH1A1ALOX15TDP1RECQLHSD17B10
SCHEMBL30336957 0.88 ALDH1A1 (0.46) ALDH1A1ALOX15TDP1RECQLHSD17B10
SCHEMBL16431292 0.87 ALDH1A1 (0.52) ALDH1A1ALOX15TDP1RECQLHSD17B10
SCHEMBL2835438 0.87 ALDH1A1 (0.52) ALDH1A1ALOX15TDP1RECQLHSD17B10
SCHEMBL14032036 0.87 ALDH1A1 (0.52) ALDH1A1ALOX15TDP1RECQLHSD17B10
SCHEMBL12192901 0.87 ALDH1A1 (0.46) ALDH1A1ALOX15TDP1RECQLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7105634-B2 Genetic constructs encoding carotenoid biosynthetic enzymes E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-09-12 — — US claimed
EP-4551713-A1 RECOMBINANT HOST CELLS PRODUCING IRONES AND USES THEREOF MUSEUM NATIONAL D'HISTOIRE NATURELLE (FR) 2025-05-14 — — EP disclosed
CN-119242603-B Dehydrosqualene desaturase mutant and application thereof 华南理工大学 2025-04-22 — — CN disclosed
CN-119242603-A Dehydrosqualene desaturase mutant and application thereof 华南理工大学 2025-01-03 — — CN disclosed
US-20240423911-A1 EMULSION COMPOSITION ASTAREAL CO., LTD. (JP) 2024-12-26 — — US disclosed
WO-2024008889-A1 RECOMBINANT HOST CELLS PRODUCING IRONES AND USES THEREOF MUSEUM NATIONAL D'HISTOIRE NATURELLE (FR) 2024-01-11 — — WO disclosed
EP-4303308-A1 RECOMBINANT HOST CELLS PRODUCING IRONES AND USES THEREOF MUSEUM NATIONAL D'HISTOIRE NATURELLE (FR) 2024-01-10 — — EP disclosed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 — — US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 — — US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 — — US disclosed
EP-1283826-A4 A PROCESS FOR PREPARING CAROTENOID POLYENE CHAIN COMPOUNDS AND INTERMEDIATES FOR PREPARING THE SAME KOO SANGHO (KR) 2005-11-23 — — EP disclosed
WO-2004101746-A2 PRODUCTION OF CAROTENOIDS IN MICROORGANISMS REGENTS FOR THE UNIVERSITY OF MINNESOTA (US) 2004-11-25 — — WO disclosed
EP-1476546-A2 FUNCTIONALIZATION OF CAROTENOID COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-11-17 — — EP disclosed
US-6747166-B2 ISOPRENE OXIDATION AND REACTION WITH MERCAPTOBENZNE TO FORM ALLYLIC SULFIDES; CHAIN EXTENSION AND RAMBERG-BAKLUND REACTION; LYCOPENE Koo, Sangho (KR) 2004-06-08 — — US disclosed
WO-2003101184-A2 CAROTENOID SYNTHESIS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2003-12-11 — — WO disclosed
US-20030182687-A1 Functionalization of carotenoid compounds E.I. DU PONT DE NEMOURS AND COMAPANY 2003-09-25 — — US disclosed
WO-2003068917-A2 FUNCTIONALIZATION OF CAROTENOID COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-08-21 — — WO disclosed
US-20030100785-A1 Process for preparing carotenoid polyene chain compounds and intermediates for preparing the same SK INNOVATION CO., LTD. (KR) 2003-05-29 — — US disclosed
EP-1283826-A1 A PROCESS FOR PREPARING CAROTENOID POLYENE CHAIN COMPOUNDS AND INTERMEDIATES FOR PREPARING THE SAME Koo, Sangho (KR) 2003-02-19 — — EP disclosed
WO-2001064630-A1 A PROCESS FOR PREPARING CAROTENOID POLYENE CHAIN COMPOUNDS AND INTERMEDIATES FOR PREPARING THE SAME SK CORPORATION (KR) 2001-09-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030182687-A1 Functionalization of carotenoid compounds FASN, ALOX12, ADH1A ALDH1A1 16/4885ALOX15 8/4885TDP1 4176/4885
US-20030100785-A1 Process for preparing carotenoid polyene chain compounds and intermediates for preparing the same CBS, STS, DHPS ALDH1A1 1342/4885ALOX15 63/4885TDP1 4524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.