Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456362 | 1.00 | ALDH1A1 (0.48) | ALDH1A1ALOX15TDP1TSHRRECQL | |
| SCHEMBL18531566 | 0.97 | ALDH1A1 (0.44) | ALDH1A1ALOX15TDP1TSHRRECQL | |
| SCHEMBL1071946 | 0.97 | ALDH1A1 (0.44) | ALDH1A1ALOX15TDP1TSHRRECQL | |
| SCHEMBL1071948 | 0.97 | ALDH1A1 (0.44) | ALDH1A1ALOX15TDP1TSHRRECQL | |
| SCHEMBL12216264 | 0.97 | ALDH1A1 (0.44) | ALDH1A1ALOX15TDP1TSHRRECQL | |
| SCHEMBL13885810 | 0.90 | ALDH1A1 (0.52) | ALDH1A1ALOX15TDP1TSHRRECQL | |
| SCHEMBL5873700 | 0.85 | ALDH1A1 (0.48) | ALDH1A1ALOX15TDP1TSHRRECQL | |
| SCHEMBL5873701 | 0.85 | ALDH1A1 (0.48) | ALDH1A1ALOX15TDP1TSHRRECQL | |
| SCHEMBL4623531 | 0.84 | ALDH1A1 (0.56) | ALDH1A1ALOX15TDP1TSHRRECQL | |
| SCHEMBL4286077 | 0.84 | ALDH1A1 (0.56) | ALDH1A1ALOX15TDP1TSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237443-A1 | MUTANT NQ-RHODOPSIN KR 2 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2017-11-01 | — | — | EP | claimed |
| WO-2016102677-A1 | MUTANT NQ-RHODOPSIN KR 2 | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2016-06-30 | — | — | WO | claimed |
| EP-2614079-B1 | MUTANT CHANNELRHODOPSIN 2 | MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V (DE) | 2015-07-15 | — | — | EP | claimed |
| US-8748578-B2 | Mutant channelrhodopsin 2 | Max-Planck-Gesellschaft zur Foerderrung der Wissenschaften e.V. (DE) | 2014-06-10 | — | — | US | claimed |
| EP-2055714-B1 | Biological photo-receptors as directly light-controlled ion channels and their use | MAX PLANCK GESELLSCHAFT (DE) | 2014-05-07 | — | — | EP | claimed |
| US-8647870-B2 | Use of biological photoreceptors as directly light-activated ion channels | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2014-02-11 | — | — | US | claimed |
| US-20130281379-A1 | MUTANT CHANNELRHODOPSIN 2 | Max-Planck-Gesellschaft zur Foerderung der Wissenschaftern e.V. (DE) | 2013-10-24 | — | — | US | claimed |
| EP-2614079-A1 | MUTANT CHANNELRHODOPSIN 2 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-07-17 | — | — | EP | claimed |
| US-20130017597-A1 | USE OF BIOLOGICAL PHOTORECEPTORS AS DIRECTLY LIGHT-ACTIVATED ION CHANNELS | MAX-PLANCK-GESEL. ZUR FOERDERUNG DER WISSEN. EV. (DE) | 2013-01-17 | — | — | US | claimed |
| US-8202699-B2 | Use of biological photoreceptors as directly light-activated ion channels | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2012-06-19 | — | — | US | claimed |
| WO-2012032103-A1 | MUTANT CHANNELRHODOPSIN 2 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2012-03-15 | — | — | WO | claimed |
| US-20110086421-A1 | USE OF BIOLOGICAL PHOTORECEPTORS AS DIRECTLY LIGHT-ACTIVATED ION CHANNELS | MAX-PLANCK-GESEL.ZUR FOERDERUNG DER WISSEN. E.V. (DE) | 2011-04-14 | — | — | US | claimed |
| US-7824869-B2 | Use of biological photoreceptors as directly light-activated ion channels | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2010-11-02 | — | — | US | claimed |
| EP-2112510-A1 | Use of biological photo-receptors as direct light-controlled ion channels | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2009-10-28 | — | — | EP | claimed |
| EP-2055714-A2 | Biological photo-receptors as directly light-controlled ion channels and their use | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2009-05-06 | — | — | EP | claimed |
| EP-1492881-B1 | USE OF BIOLOGICAL PHOTORECEPTORS AS DIRECTLY LIGHT-ACTIVATED ION CHANNELS | MAX PLANCK GESELLSCHAFT (DE) | 2008-10-22 | — | — | EP | claimed |
| US-20050202398-A1 | Use of biological photoreceptors as directly light-activated ion channels | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2005-09-15 | — | — | US | claimed |
| EP-1492881-A2 | USE OF BIOLOGICAL PHOTORECEPTORS AS DIRECTLY LIGHT-ACTIVATED ION CHANNELS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2005-01-05 | — | — | EP | claimed |
| WO-2003084994-A2 | USE OF BIOLOGICAL PHOTORECEPTORS AS DIRECTLY LIGHT-ACTIVATED ION CHANNELS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2003-10-16 | — | — | WO | claimed |
| US-20240165198-A1 | OPTOGENETIC VISUAL RESTORATION USING CHRIMSON | SORBONNE UNIVERSITE (FR) | 2024-05-23 | — | — | US | disclosed |
| EP-4223768-A1 | NOVEL MUTANT BACTERIORHODOPSIN-LIKE-CHANNELRHODOPSIN ION CHANNEL | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin (DE) | 2023-08-09 | — | — | EP | disclosed |
| CN-109790209-B | Mutant photoinduced ion channels of Chrismson | 马克斯-普朗克科学促进协会 | 2022-10-04 | — | — | CN | disclosed |
| US-11384132-B2 | Mutant light-inducible ion channel of chrimson | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | 2022-07-12 | — | — | US | disclosed |
| WO-2021086219-A1 | LIGHT-GATED PENTAMERIC CHANNEL - A NEW OPTOGENETIC TOOL | FORSCHUNGSZENTRUM JÜLICH, INSTITUTE OF COMPLEX SYSTEMS (DE) | 2021-05-06 | — | — | WO | disclosed |
| US-20200115419-A1 | NEW OPTOGENETIC TOOL | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2020-04-16 | — | — | US | disclosed |
| EP-3609518-A1 | NEW OPTOGENETIC TOOL | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2020-02-19 | — | — | EP | disclosed |
| US-20190269755-A1 | OPTOGENETIC VISUAL RESTORATION USING CHRIMSON | GENSIGHT BIOLOGICS SA (FR) | 2019-09-05 | — | — | US | disclosed |
| US-20190218256-A1 | MUTANT LIGHT-INDUCIBLE ION CHANNEL OF CHANNELRHODOPSIN | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2019-07-18 | — | — | US | disclosed |
| US-20190218271-A1 | MUTANT LIGHT-INDUCIBLE ION CHANNEL OF CHRIMSON | GEORG-AUGUST-UNIVERSITÄT GÖTTINGEN STIFTUNG ÖFFENTLICHEN RECHTS, UNIVERSITÄTSMEDIZIN (DE) | 2019-07-18 | — | — | US | disclosed |
| EP-3464342-A1 | MUTANT LIGHT-INDUCIBLE ION CHANNEL OF CHRIMSON | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2019-04-10 | — | — | EP | disclosed |
| EP-3464341-A1 | MUTANT LIGHT-INDUCIBLE ION CHANNEL OF CHANNELRHODOPSIN | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2019-04-10 | — | — | EP | disclosed |
| WO-2018189247-A1 | NEW OPTOGENETIC TOOL | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2018-10-18 | — | — | WO | disclosed |
| US-20170362281-A1 | MUTANT NQ-RHODOPSIN KR 2 | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2017-12-21 | — | — | US | disclosed |
| WO-2017207761-A1 | MUTANT LIGHT-INDUCIBLE ION CHANNEL OF CHRIMSON | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2017-12-07 | — | — | WO | disclosed |
| WO-2017207745-A1 | MUTANT LIGHT-INDUCIBLE ION CHANNEL OF CHANNELRHODOPSIN | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2017-12-07 | — | — | WO | disclosed |
| EP-3237443-A1 | MUTANT NQ-RHODOPSIN KR 2 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016102677-A1 | MUTANT NQ-RHODOPSIN KR 2 | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2016-06-30 | — | — | WO | disclosed |
| US-9138596-B2 | Optical depolarization of cardiac tissue | CARDIAC PACEMAKERS, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| EP-2614079-B1 | MUTANT CHANNELRHODOPSIN 2 | MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V (DE) | 2015-07-15 | — | — | EP | disclosed |
| US-8748578-B2 | Mutant channelrhodopsin 2 | Max-Planck-Gesellschaft zur Foerderrung der Wissenschaften e.V. (DE) | 2014-06-10 | — | — | US | disclosed |
| EP-2055714-B1 | Biological photo-receptors as directly light-controlled ion channels and their use | MAX PLANCK GESELLSCHAFT (DE) | 2014-05-07 | — | — | EP | disclosed |
| US-8647870-B2 | Use of biological photoreceptors as directly light-activated ion channels | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2014-02-11 | — | — | US | disclosed |
| US-20130281379-A1 | MUTANT CHANNELRHODOPSIN 2 | Max-Planck-Gesellschaft zur Foerderung der Wissenschaftern e.V. (DE) | 2013-10-24 | — | — | US | disclosed |
| EP-2614079-A1 | MUTANT CHANNELRHODOPSIN 2 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-07-17 | — | — | EP | disclosed |
| US-20130017597-A1 | USE OF BIOLOGICAL PHOTORECEPTORS AS DIRECTLY LIGHT-ACTIVATED ION CHANNELS | MAX-PLANCK-GESEL. ZUR FOERDERUNG DER WISSEN. EV. (DE) | 2013-01-17 | — | — | US | disclosed |
| US-8202699-B2 | Use of biological photoreceptors as directly light-activated ion channels | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2012-06-19 | — | — | US | disclosed |
| WO-2012032103-A1 | MUTANT CHANNELRHODOPSIN 2 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2012-03-15 | — | — | WO | disclosed |
| US-20110086421-A1 | USE OF BIOLOGICAL PHOTORECEPTORS AS DIRECTLY LIGHT-ACTIVATED ION CHANNELS | MAX-PLANCK-GESEL.ZUR FOERDERUNG DER WISSEN. E.V. (DE) | 2011-04-14 | — | — | US | disclosed |
| US-7824869-B2 | Use of biological photoreceptors as directly light-activated ion channels | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2010-11-02 | — | — | US | disclosed |
| EP-2112510-A1 | Use of biological photo-receptors as direct light-controlled ion channels | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2009-10-28 | — | — | EP | disclosed |
| EP-2055714-A2 | Biological photo-receptors as directly light-controlled ion channels and their use | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2009-05-06 | — | — | EP | disclosed |
| US-20090092642-A1 | Skin and/or Hair Products, Containing Compounds With an Isoprenoid Structure | BEIERSDORF AG (DE) | 2009-04-09 | — | — | US | disclosed |
| US-20090092642-A1 | Skin and/or Hair Products, Containing Compounds With an Isoprenoid Structure | BEIERSDORF AG (DE) | 2009-04-09 | — | — | US | disclosed |
| US-20090054954-A1 | Optical depolarization of cardiac tissue | CARDIAC PACEMAKERS, INC. (US) | 2009-02-26 | — | — | US | disclosed |
| EP-1492881-B1 | USE OF BIOLOGICAL PHOTORECEPTORS AS DIRECTLY LIGHT-ACTIVATED ION CHANNELS | MAX PLANCK GESELLSCHAFT (DE) | 2008-10-22 | — | — | EP | disclosed |
| WO-2005102252-A9 | SKIN AND/OR HAIR PRODUCTS, CONTAINING COMPOUNDS WITH AN ISOPRENOID STRUCTURE | BEIERSDORF AG (DE) | 2007-01-11 | — | — | WO | disclosed |
| US-20050202398-A1 | Use of biological photoreceptors as directly light-activated ion channels | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2005-09-15 | — | — | US | disclosed |
| EP-1492881-A2 | USE OF BIOLOGICAL PHOTORECEPTORS AS DIRECTLY LIGHT-ACTIVATED ION CHANNELS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003084994-A2 | USE OF BIOLOGICAL PHOTORECEPTORS AS DIRECTLY LIGHT-ACTIVATED ION CHANNELS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2003-10-16 | — | — | WO | disclosed |
| EP-0808159-A1 | USE OR RETINOIDS TO LOWER PLASMA LEVELS OF LIPOPROTEIN (a) | WARNER-LAMBERT COMPANY (US) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024344-A1 | USE OF RETINOIDS TO LOWER PLASMA LEVELS OF LIPOPROTEIN (a) | WARNER-LAMBERT COMPANY (US) | 1996-08-15 | — | — | WO | disclosed |
| US-5489611-A | ADMINISTERING A RETINOID COMPOUND | WARNER-LAMBERT COMPANY (US) | 1996-02-06 | — | — | US | disclosed |
| US-5489611-A | ADMINISTERING A RETINOID COMPOUND | WARNER-LAMBERT COMPANY (US) | 1996-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090092642-A1 | Skin and/or Hair Products, Containing Compounds With an Isoprenoid Structure | SRD5A2, SRD5A1, CUTA | ALDH1A1 2012/4885ALOX15 222/4885TDP1 4470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.