Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 1.00 |
| ▸ | ARG2 | P78540 | 4/20 | 0.59 |
| ▸ | ARG1 | P05089 | 3/20 | 0.59 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL12867528 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL1000151 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL20362357 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL7343 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL3359527 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL9439278 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL2802757 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL15303774 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL456381 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL1645 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020135658-A1 | POLYPEPTIDE HAVING PHOSPHOLIPASE C ACTIVITY AND USE THEREOF | 丰益(上海)生物技术研发中心有限公司 | 2020-07-02 | — | — | WO | claimed |
| CN-110250349-A | A kind of big swine feed of reinforcing reducing the thickness of backfat | 正大康地阳江饲料有限公司 | 2019-09-20 | — | — | CN | claimed |
| CN-110250350-A | A kind of low small swine feed of brotein equilibrium amino acid | 正大康地阳江饲料有限公司 | 2019-09-20 | — | — | CN | claimed |
| CN-105316270-B | Engineering bacterium for catalytically producing 1, 5-pentanediamine and application thereof | 宁夏伊品生物科技股份有限公司 | 2019-01-29 | — | — | CN | claimed |
| EP-3309167-A1 | SMALL-MOLECULE POLYPEPTIDE ZY4 AND APPLICATION THEREOF | Sichuan Hetai Synlight Biotech Ltd. (CN) | 2018-04-18 | — | — | EP | claimed |
| CN-106904635-A | It is a kind of to be aided in by amino acid under dense gel rubber system and be segmented method of the crystallization coordinate system for nano molecular sieve | 吉林大学 | 2017-06-30 | — | — | CN | claimed |
| US-8501679-B2 | Cyclic, cystein-free protein | APEPTICO FORSCHUNG UND ENTWICKLUNG GMBH (AT) | 2013-08-06 | — | — | US | claimed |
| EP-2217619-B1 | CYCLIC, CYSTEIN-FREE PROTEIN | APEPTICO FORSCHUNG & ENTWICKLUNG GMBH (AT) | 2012-11-07 | — | — | EP | claimed |
| US-20110105414-A1 | CYCLIC, CYSTEIN-FREE PROTEIN | APEPTICO FORSCHUNG UND ENTWICKLUNG GMBH (AT) | 2011-05-05 | — | — | US | claimed |
| EP-2217619-A1 | CYCLIC, CYSTEIN-FREE PROTEIN | Apeptico Forschung Und Entwicklung Gmbh (AT) | 2010-08-18 | — | — | EP | claimed |
| EP-1740698-B1 | RECOMBINANTLY MODIFIED PLASMIN | TALECRIS BIOTHERAPEUTICS INC (US) | 2010-08-04 | — | — | EP | claimed |
| WO-2009073909-A1 | CYCLIC, CYSTEIN-FREE PROTEIN | APEPTICO FORSCHUNG UND ENTWICKLUNG GMBH (AT) | 2009-06-18 | — | — | WO | claimed |
| CN-1325063-C | L-amino acid water-soluble pearl powder and its preparing method | SONG TINGSHENG (CN) | 2007-07-11 | — | — | CN | claimed |
| CN-1308690-C | Novel method and kit for sequencing polypeptides | PROCTER & GAMBLE (US) | 2007-04-04 | — | — | CN | claimed |
| CN-1709282-A | L-amino acid water-soluble pearl powder and its preparing method | SONG TINGSHENG (CN) | 2005-12-21 | — | — | CN | claimed |
| CN-1551984-A | Novel method and kit for sequencing polypeptides | — | 2004-12-01 | — | — | CN | claimed |
| US-11826399-B2 | Chlorotoxin agents and uses thereof | EISAI INC. (US) | 2023-11-28 | — | — | US | disclosed |
| CN-116694539-B | Lactobacillus plantarum J26 as direct vat set starter, and preparation method and application thereof | 东北农业大学 | 2023-11-17 | — | — | CN | disclosed |
| US-5227166-A | Core of active material, stable coating of lecithin, inorganic salt, and hardened oil or wax | AJINOMOTO CO., INC. (JP) | 1993-07-13 | — | — | US | disclosed |
| WO-1992008341-A1 | NOVEL PRODUCTION METHOD FOR CORN WITH ENHANCED QUALITY GRAIN TRAITS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11826399-B2 | Chlorotoxin agents and uses thereof | NRP1, LCP1, CLSPN | GSR 3695/4885ARG2 1803/4885ARG1 904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.