SCHEMBL4564170

SCHEMBL4564170

CCCc1ccc(OP(=O)(CCCCO)CCCCO)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
CYP2C19 P33261 1/20 0.41
PPARA Q07869 1/20 0.39
CYP4A11 Q02928 2/20 0.39
CYP4F2 P78329 1/20 0.39
ALDH1A1 P00352 2/20 0.38
PLK1 P53350 1/20 0.38
S1PR1 P21453 5/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
USP2 O75604 1/20 0.38
LMNA P02545 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
CASP1 P29466 1/20 0.38
SLCO1B3 Q9NPD5 1/20 0.38
SLCO1B1 Q9Y6L6 1/20 0.38
S1PR3 Q99500 3/20 0.37
S1PR4 O95977 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4564023 0.95 THRB (0.43) THRBSMN1; SMN2CYP2C19PPARACYP4A11
SCHEMBL4564981 0.93 S1PR1 (0.43) THRBSMN1; SMN2CYP2C19PPARACYP4A11
SCHEMBL4564737 0.88 ALDH1A1 (0.43) THRBSMN1; SMN2CYP2C19PPARAALDH1A1
SCHEMBL4563900 0.88 SMN1; SMN2 (0.54) SMN1; SMN2CYP2C19PPARACYP4A11CYP4F2
SCHEMBL4564589 0.83 SMN1; SMN2 (0.56) SMN1; SMN2CYP2C19PPARACYP4A11ALDH1A1
SCHEMBL4564600 0.81 TSHR (0.50) KMT2AMEN1LMNACYP3A4
SCHEMBL4564647 0.77 SRC (0.48) CYP2C19ALDH1A1KMT2AMEN1
SCHEMBL4563939 0.76 CYP3A4 (0.52) KMT2AMEN1LMNACYP3A4
SCHEMBL1100625 0.75 BLM (0.58) THRBSMN1; SMN2CYP2C19ALDH1A1PLK1
SCHEMBL1592157 0.75 CYP3A4 (0.54) THRBSMN1; SMN2CYP2C19ALDH1A1PLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed