Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4563900 | 0.95 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP2C19POLBALDH1A1LMNA | |
| SCHEMBL4564023 | 0.87 | THRB (0.43) | SMN1; SMN2CYP2C19ALDH1A1LMNAPLK1 | |
| SCHEMBL4564737 | 0.86 | ALDH1A1 (0.43) | SMN1; SMN2CYP2C19ALDH1A1LMNAHPGD | |
| SCHEMBL4563939 | 0.83 | CYP3A4 (0.52) | LMNAMAPTHPGD | |
| SCHEMBL4564170 | 0.83 | THRB (0.42) | SMN1; SMN2CYP2C19ALDH1A1LMNAPLK1 | |
| SCHEMBL4564981 | 0.81 | S1PR1 (0.43) | SMN1; SMN2CYP2C19ALDH1A1LMNAHPGD | |
| SCHEMBL4564484 | 0.79 | SRC (0.50) | CYP2C19ALDH1A1SRC | |
| SCHEMBL4564600 | 0.78 | TSHR (0.50) | LMNAMAPTHPGD | |
| SCHEMBL1101448 | 0.74 | CYP2C19 (0.72) | SMN1; SMN2CYP2C19POLBALDH1A1RXRA | |
| SCHEMBL2150400 | 0.74 | SMN1; SMN2 (0.72) | SMN1; SMN2CYP2C19POLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612148-B2 | Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer | TSRC CORPORATION (TW) | 2009-11-03 | — | — | US | disclosed |
| US-20080146733-A1 | Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer | TSRC CORPORATION (TW) | 2008-06-19 | — | — | US | disclosed |