Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL576170 | 0.81 | ACHE (0.40) | ACHEESR1ESR2SMN1; SMN2CES2 | |
| SCHEMBL577112 | 0.81 | ACHE (0.40) | ACHEESR1ESR2SMN1; SMN2CES2 | |
| SCHEMBL17384528 | 0.79 | ACHE (0.39) | ACHEESR1ESR2SMN1; SMN2CES2 | |
| SCHEMBL28339570 | 0.77 | ACHE (0.37) | ACHEESR1ESR2SMN1; SMN2CES2 | |
| SCHEMBL254224 | 0.74 | — | — | |
| SCHEMBL24603806 | 0.74 | CYP2C9 (0.36) | ACHEESR1ESR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL900553 | 0.74 | ACHE (0.34) | ACHEESR1ESR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL17384531 | 0.74 | ALDH1A1 (0.38) | ACHESMN1; SMN2TP53ALDH1A1GAA | |
| SCHEMBL2051708 | 0.73 | — | — | |
| SCHEMBL19774033 | 0.72 | ALDH1A1 (0.34) | ACHESMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1426365-B9 | 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME | MITSUI CHEMICALS AGRO INC (JP) | 2009-10-21 | — | — | EP | disclosed |
| EP-1426365-B1 | 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME | SANKYO AGRO CO LTD (JP) | 2009-07-15 | — | — | EP | disclosed |