Dihydrocinnamaldehyde

Dihydrocinnamaldehyde

SCHEMBL4564483

CCC=O.O=CCCc1ccccc1.O=[PH2]O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GPR52 Q9Y2T5 12/20 0.41
ALDH1A1 P00352 1/20 0.40
KEAP1 Q14145 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ADH1B P00325 1/20 0.37
ADH1C P00326 1/20 0.37
ADH1A P07327 1/20 0.37
ADH7 P40394 1/20 0.37
GRIK1 P39086 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dihydrocinnamaldehyde SCHEMBL8109306 0.91 ADH1B (0.43) GPR52ALDH1A1KEAP1ADH1BADH1C
Dihydrocinnamaldehyde SCHEMBL29052009 0.85 TDP1 (0.48) GPR52ALDH1A1KEAP1TDP1ADH1B
Dihydrocinnamaldehyde SCHEMBL1335 0.82 ADH1B (0.50) GPR52ALDH1A1KEAP1TDP1ADH1B
Butanal SCHEMBL4564646 0.81 ADRA1A (0.41) ALDH1A1TDP1
Propionaldehyde SCHEMBL4564588 0.81 GABRA1 (0.35) ALDH1A1TDP1
Dihydrocinnamaldehyde SCHEMBL19810527 0.80 ADH1B (0.48) GPR52ALDH1A1KEAP1TDP1ADH1B
Dihydrocinnamaldehyde SCHEMBL11053918 0.80 ADH1B (0.48) GPR52ALDH1A1KEAP1TDP1ADH1B
Dihydrocinnamaldehyde SCHEMBL5791873 0.80 ADH1B (0.48) GPR52ALDH1A1KEAP1TDP1ADH1B
Dihydrocinnamaldehyde SCHEMBL11053817 0.80 ADH1B (0.48) GPR52ALDH1A1KEAP1TDP1ADH1B
Propionaldehyde SCHEMBL4564022 0.79 PPARG (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed